The Association between Dietary Magnesium Intake and Telomere Length in Adults with Hypertension
Zhao G, Guo D, Li L, Yang C, Dong J
The journal of nutrition, health & aging · 5 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Estudio transversal (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2022-11-01 · J Nutr Health Aging · vol. 26 · número 11 · págs. 1010–1015
- Editorial
- Springer Science+Business Media
- Citado
- 6 citas · más que el 67% de estudios similares · 0.7× el promedio de su campo
- Referencias
- 45 trabajos
- Acceso
- Acceso abierto (revista híbrida) · CC-BY-NC-ND
- Áreas de investigación
- Telomeres, Telomerase, and Senescence · Menopause: Health Impacts and Treatments · Birth, Development, and Health
- Palabras clave
- National Health and Nutrition Examination Survey, Medicine, Telomere, Micronutrient, Magnesium, Bayesian multivariate linear regression, Internal medicine, Physiology, Endocrinology, Linear regression, Environmental health, Biology, Population, Chemistry, Pathology, Biochemistry
- MeSH
- telomere, humans, hypertension, magnesium, uric acid, nutrition surveys, female, male
5 autores
- Ge Zhao🇨🇳First Affiliated Hospital of Zhengzhou University
- Danfeng Guo🇨🇳First Affiliated Hospital of Zhengzhou University
- L. Li🇨🇳First Affiliated Hospital of Zhengzhou University
- Chih‐Wei Yang🇨🇳First Affiliated Hospital of Zhengzhou University
- Jianzeng Dong🇨🇳 · autor de correspondenciaCapital Medical University; Beijing Anzhen Hospital; First Affiliated Hospital of Zhengzhou University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Dietary micronutrients are significantly associated with telomere length, as shown in multiple studies. However, no study has investigated the association between magnesium intake and telomere length in adults with hypertension.
Methods
Participants were included from the National Health and Nutrition Examination Survey (NHANES) in 1999-2000 and 2001-2002. Dietary magnesium intake was assessed using the 24 - hour recall method and the telomere length of leukocytes was measured using polymerase chain reaction (PCR). A multivariate regression model was then used to assess the association between dietary magnesium intake and telomere length in adults with hypertension.
Results
Our final analysis included 2199 hypertensive adults (46.79% males) with a mean dietary magnesium intake of 254.82±133.47 mg/day. Linear regression, adjusted for race, sex, age, smoking, uric acid, and other variables, showed that every 1 mg increase in dietary magnesium intake was associated with a 0.20 (95% CI: 0.01, 0.39, p = 0.043) longer telomere length in all participants. In the ≥45 years age group, there was a statistically significant association between the telomere length and dietary magnesium (95% CI: 0.16, 0.63, p <0.001).
Conclusions
This study suggests that increased magnesium intake is associated with a longer telomere length in hypertensive adults, especially in those ≥45 years of age. However, further research is needed to determine a causal relationship.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC-ND).
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