The effect of topical olive oil dressing on the healing of grade 1 and 2 diabetic foot ulcers: An assessor-blind randomized controlled trial in type 2 diabetes patients
Abdoli A, Shahbazi R, Zoghi G, Davoodian P, Kheirandish S, Azad M, Kheirandish M
Diabetes & metabolic syndrome · 7 citas
Etiquetas de revisión
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Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2022-11-24 · Diabetes Metab Syndr · vol. 16 · número 12 · pág. 102678
- Editorial
- Elsevier BV
- Citado
- 22 citas · más que el 90% de estudios similares · 2.4× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 27 trabajos
- Acceso
- De pago
- Áreas de investigación
- Diabetic Foot Ulcer Assessment and Management · Wound Healing and Treatments · Skin Diseases and Diabetes
- Palabras clave
- diabetic foot ulcer, topical dressings, wound healing, type 2 diabetes, oral antibiotics, wound irrigation
- MeSH
- humans, olea, diabetic foot, diabetes mellitus, type 2, bandages, wound healing, iran, olive oil
7 autores
- Aminreza Abdoli🇮🇷Hormozgan University of Medical Sciences
- Roghayeh Shahbazi🇨🇦University of Ottawa
- Ghazal Zoghi🇮🇷Hormozgan University of Medical Sciences
- Parivash Davoodian🇮🇷Hormozgan University of Medical Sciences
- Somayeh Kheirandish🇮🇷 · autor de correspondenciaHormozgan University of Medical Sciences
- Mohsen Azad🇮🇷Hormozgan University of Medical Sciences
- Masoumeh Kheirandish🇮🇷 · autor de correspondenciaHormozgan University of Medical Sciences
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background and aims
We aimed to compare the effect of topical olive oil dressing plus standard care with standard care alone on the treatment of grade 1 and 2 diabetic foot ulcers (DFUs) in type 2 diabetes mellitus (T2DM) patients.
Methods
This assessor-blind randomized controlled trial included 60 T2DM patients with DFU referred to the Diabetes Clinic of Shahid Mohammadi Hospital, Bandar Abbas, Iran, from February 21 to August 22, 2017. Patients were randomly assigned to intervention (n = 30) and control (n = 30) groups. The intervention group received standard care, including wound irrigation with normal saline and oral antibiotics plus daily topical olive oil dressing for four weeks, and the control group only received standard care. The wound healing assessment scale (wound degree, color, drainage, and surrounding tissue healing) was recorded weekly and the total wound status was determined at the end of the study.
Results
Treatment with olive oil led to significantly higher scores of ulcer degree, color, drainage, and surrounding tissue healing at weeks one, two, three and four in the olive oil group than in the control group (P < 0.001). Also, the total wound status score was higher in the olive oil group compared to the control group (P < 0.001). The proportions of completely healed, partially healed, and unhealed wounds were 76.6%, 23.3% and 0% in the intervention group, and 0%, 93.3% and 6.7% in the control group, respectively.
Conclusions
Topical olive oil dressing promoted the healing of DFU and it can be recommended as a safe and effective treatment in this regard.
Trial registration
Iranian Registry of Clinical Trials (IRCT), IRCT20150607022585N4. Registered 05/12/2018. Retrospectively registered, https://www.irct.ir/trial/19460.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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