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Ensayo controlado aleatorizado2023

Early time-restricted eating affects weight, metabolic health, mood, and sleep in adherent completers: A secondary analysis

Steger FL, Jamshed H, Bryan DR, Richman JS, Warriner AH, Hanick CJ, Martin CK, Salvy SJ, Peterson CM

Obesity (Silver Spring, Md.) · 63 citas

Cómo se estudió

Diseño
Ensayo controlado aleatorizado (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento

Quién lo pagó

Financiación
Financiación independiente
Gobierno
National Heart, Lung, and Blood Institute
Gobierno
National Institute of General Medical Sciences
Gobierno
National Institute of Diabetes and Digestive and Kidney Diseases
Gobierno
National Center for Advancing Translational Sciences
Gobierno
NIDDK NIH HHS
Gobierno
NCATS NIH HHS
Gobierno
NIGMS NIH HHS
Gobierno
NHLBI NIH HHS
Subvenciones
National Institute of Diabetes and Digestive and Kidney Diseases (P30DK079626); National Institute of General Medical Sciences (U54‐ GM104940); National Heart, Lung, and Blood Institute (T32HL105349)); National Center for Advancing Translational Sciences (KL2 TR001419); National Center for Advancing Translational Sciences (TL1 TR001418); National Center for Advancing Translational Sciences (UL1 TR001418); National Institute of Diabetes and Digestive and Kidney Diseases (P30 DK-072476); National Institute of Diabetes and Digestive and Kidney Diseases (P30-DK-056336)

Según 8 financiadores declarados.

Publicación

Publicado
2022-12-14 · Obesity (Silver Spring) · vol. 31 · número S1 · págs. 96–107
Editorial
Wiley
Citado
73 citas · más que el 98% de estudios similares · 6.1× el promedio de su campo
Impacto
Entre el 10 % más citado de su campo
Referencias
47 trabajos
Acceso
Acceso abierto (copia en repositorio)
Áreas de investigación
Dietary Effects on Health · Enhanced Recovery After Surgery · Circadian rhythm and melatonin
Palabras clave
Medicine, Weight loss, Mood, Anger, Obesity, Internal medicine, Heart rate, Body weight, Randomized controlled trial, Physical therapy, Endocrinology, Blood pressure, Psychiatry
MeSH
humans, cardiovascular diseases, obesity, weight loss, fasting, sleep, body composition, eating, adult, aged, middle aged

9 autores

  • Felicia L. Steger🇺🇸University of Alabama at Birmingham; University of Kansas Medical Center
  • Humaira Jamshed🇺🇸🇵🇰University of Alabama at Birmingham; Habib University
  • David R. Bryan🇺🇸University of Alabama at Birmingham
  • Joshua Richman🇺🇸University of Alabama at Birmingham
  • Amy H. Warriner🇺🇸University of Alabama at Birmingham
  • Cody J. Hanick🇺🇸University of Alabama at Birmingham
  • Corby K. Martin🇺🇸Pennington Biomedical Research Center
  • Sarah‐Jeanne Salvy🇺🇸Cedars-Sinai Medical Center
  • Courtney M. Peterson🇺🇸 · autor de correspondenciaUniversity of Alabama at Birmingham

Resumen

El texto original del estudio, en el idioma en que se publicó.

Objective

Data are mixed on whether intermittent fasting improves weight loss and cardiometabolic health. Here, the effects of time-restricted eating (TRE) in participants who consistently adhered ≥5 d/wk every week were analyzed.

Methods

Ninety patients aged 25 to 75 years old with obesity were randomized to early TRE (eTRE; 8-hour eating window from 07:00 to 15:00) or a control schedule (≥12-hour window) for 14 weeks. A per-protocol analysis of weight loss, body composition, cardiometabolic health, and other end points was performed.

Results

Participants who adhered to eTRE ≥5 d/wk every week had greater improvements in body weight (-3.7 ± 1.2 kg; p = 0.003), body fat (-2.8 ± 1.3 kg; p = 0.04), heart rate (-7 ± 3 beats/min; p = 0.02), insulin resistance (-2.80 ± 1.36; p = 0.047), and glucose (-9 ± 5 mg/dL; p = 0.047) relative to adherers in the control group. They also experienced greater improvements in mood, including fatigue and anger; however, they self-reported sleeping less and taking longer to fall asleep.

Conclusions

For those who can consistently adhere at least 5 d/wk, eTRE is a valuable approach for improving body weight, body fat, cardiometabolic health, and mood. Further research is needed to determine whether eTRE's effects of shortening sleep but reducing fatigue are healthful or not.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.

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