Lanzamiento Enero 2027

Revisión sistemática2023Financiación no declarada

Umbrella review of time-restricted eating on weight loss, fasting blood glucose, and lipid profile

Chew HSJ, Ang WHD, Tan ZYA, Ang WW, Chan KS, Lau Y

Nutrition reviews · 24 citas

Etiquetas de revisión

Financiación no declarada

Datos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.

Cómo se estudió

Diseño
Revisión sistemática (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento

Quién lo pagó

Financiación
Financiación no declarada

Publicación

Publicado
2022-12-15 · Nutr Rev · vol. 81 · número 9 · págs. 1180–1199
Editorial
Oxford University Press
Citado
25 citas · más que el 92% de estudios similares · 2.7× el promedio de su campo
Impacto
Entre el 10 % más citado de su campo
Referencias
79 trabajos
Acceso
De pago
Áreas de investigación
Dietary Effects on Health · Enhanced Recovery After Surgery · Genetics, Aging, and Longevity in Model Organisms
Palabras clave
Overweight, Meta-analysis, Medicine, Context (archaeology), Weight loss, Obesity, Internal medicine, Cholesterol, Systematic review, Blood lipids, Endocrinology, Data extraction, MEDLINE, Biology, Biochemistry
MeSH
humans, weight loss, blood glucose, fasting, cholesterol, ldl, systematic reviews as topic

6 autores

  • Han Shi Jocelyn Chew🇸🇬National University of Singapore
  • Wei How Darryl Ang🇸🇬National University of Singapore
  • Zhen Yang Abel Tan🇸🇬National University of Singapore
  • Wen Wei Ang🇸🇬National University of Singapore
  • Kin Sun Chan🇲🇴University of Macau; City University of Macau
  • Ying Lau🇸🇬 · autor de correspondenciaNational University of Singapore

Resumen

El texto original del estudio, en el idioma en que se publicó.

Context

A growing number of systematic reviews with meta-analyses have examined the effectiveness of time-restricted eating (TRE) in reducing weight and improving fasting blood glucose and lipid profiles. However, mixed results have been found, and its effectiveness remains uncertain.

Objective

This umbrella review aimed to summarize systematic reviews that (1) examine the effects of TRE on weight loss, fasting blood glucose, total cholesterol, triglycerides, high-density-lipoprotein cholesterol (HDL-C) and low-density-lipoprotein cholesterol (LDL-C) in individuals with overweight and obesity; and (2) compare the effect sizes on these outcomes between conventional TRE and Ramadan fasting.

Data sources

A total of 11 databases were searched from inception until March 11, 2022.

Data extraction

Two independent reviewers performed article selection, data extraction, and quality assessment.

Data analysis

Seven systematic reviews with 30 unique meta-analyses involving 7231 participants from 184 primary studies were included. The quality of each review was evaluated as moderate (14.3%) or critically low (85.7%) according to the Assessment of Multiple Systematic Reviews 2. The degree of overlap was rated as slight for all outcomes (corrected cover area = 1.04%-4.27%). Meta-analyses at the meta-data level suggest that TRE is beneficial for reducing weight (P = .006) and fasting blood glucose (P < .01). Meta-analyses at the primary study level suggest that the effect on LGL-C was significant (P = .03). Subgroup analyses revealed greater effects in lowering fasting blood glucose, total cholesterol, and LDL-C from Ramadan fasting than from conventional TRE. The credibility of evidence was rated as suggestive (3.3%), weak (36.7%) or nonsignificant (60%) using a classification method.

Conclusion

TRE may complement usual care and reduce body weight and fasting blood glucose. Rigorous randomized controlled trials with long-term assessments in a wide range of populations are warranted.

Systematic review registration

PROSPERO registration no. CRD42022325657.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.

Confianza de la comunidad

Cargando…

¿Cuánto confías en los hallazgos de este estudio?

0 · nada10 · totalmente

Comentarios

¿Algo está mal aquí?

Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.

Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.