Sex-Specific Associations of Red Meat and Processed Meat Consumption with Serum Metabolites in the UK Biobank
Fan B, Zhao JV
Nutrients · 4 citas
Cómo se estudió
- Diseño
- Estudio transversal (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Medical Research Council
- Subvenciones
- Medical Research Council (MC_PC_17228)
Según 1 financiador declarado y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2022-12-14 · Nutrients · vol. 14 · número 24 · pág. 5306
- Editorial
- Multidisciplinary Digital Publishing Institute
- Citado
- 5 citas · más que el 76% de estudios similares · 1.0× el promedio de su campo
- Referencias
- 21 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Nutritional Studies and Diet · Meat and Animal Product Quality · Consumer Attitudes and Food Labeling
- Palabras clave
- Red meat, Biobank, Confounding, Polyunsaturated fatty acid, Medicine, Biology, Food science, Fatty acid, Internal medicine, Biochemistry, Genetics
- MeSH
- humans, diet, risk factors, meat, meat products, biological specimen banks, female, male, red meat, united kingdom
2 autores
- Bohan Fan🇭🇰University of Hong Kong
- Jie V. Zhao🇭🇰 · autor de correspondenciaUniversity of Hong Kong
Resumen
El texto original del estudio, en el idioma en que se publicó.
Red meat consumption has been found to closely related to cardiometabolic health, with sex disparity. However, the specific metabolic factors corresponding to red meat consumption in men and women have not been examined previously. We analyzed the sex-specific associations of meat consumption, with 167 metabolites using multivariable regression, controlling for age, ethnicity, Townsend deprivation index, education, physical activity, smoking, and drinking status among ~79,644 UK Biobank participants. We also compared the sex differences using an established formula. After accounting for multiple testing with false discovery rate < 5% and controlling for confounders, the positive associations of unprocessed red meat consumption with branched-chain amino acids and several lipoproteins, and the inverse association with glycine were stronger in women, while the positive associations with apolipoprotein A1, creatinine, and monounsaturated fatty acids were more obvious in men. For processed meat, the positive associations with branched-chain amino acids, several lipoproteins, tyrosine, lactate, glycoprotein acetyls and inverse associations with glutamine, and glycine were stronger in women than in men. The study suggests that meat consumption has sex-specific associations with several metabolites. This has important implication to provide dietary suggestions for individuals with or at high risk of cardiometabolic disease, with consideration of sex difference.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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