Association of dietary magnesium intake and glycohemoglobin with mortality risk in diabetic patients
Wang HW, Huang YT, Jiang MY
PloS one · 6 citas
Cómo se estudió
- Diseño
- Estudio de cohortes (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Chi Mei Medical Center
- Subvenciones
- Chi Mei Medical Center (CMFHR11129)
Según 1 financiador declarado y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2022-12-28 · PLoS One · vol. 17 · número 12 · pág. e0277180
- Editorial
- Public Library of Science
- Citado
- 11 citas · más que el 72% de estudios similares · 1.0× el promedio de su campo
- Referencias
- 32 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Magnesium in Health and Disease · Parathyroid Disorders and Treatments · Potassium and Related Disorders
- Palabras clave
- Medicine, Interquartile range, Diabetes mellitus, National Health and Nutrition Examination Survey, Population, Internal medicine, Cause of death, Endocrinology, Environmental health, Disease
- MeSH
- humans, cardiovascular diseases, diabetes mellitus, magnesium, diet, nutrition surveys, risk factors, prospective studies, adult, middle aged, female, male, glycated hemoglobin
3 autores
- Hung‐Wei Wang🇹🇼Chi Mei Medical Center
- Yun‐Ting Huang🇹🇼Chi Mei Medical Center
- Ming‐Yan Jiang🇹🇼 · autor de correspondenciaChi Mei Medical Center; Chia Nan University of Pharmacy and Science
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Dietary magnesium intake inversely correlated to risk of death in general population. However, it is relatively unknown whether the beneficial effect remains significant in individuals with diabetes. Our study purpose is to evaluate the association of dietary magnesium intake with mortality risk in diabetic population.
Methods
The study population is recruited from 2003-2014 National Health and Nutrition Examination Survey, totaling 2,045 adults with diabetes being included. Participants were divided based on glycohemoglobin (HbA1c 250mg/day) ascertained by 24-hour dietary recall interviews.
Results
The average age of the study population was 52.9±10.1 years, with 49.1% being male. During a median follow-up of 77.0 months (interquartile range: 45.0-107.0 months), a total of 223 participants died (1.5 per 1000 person-months). Our results showed that individuals with lower dietary magnesium intake (≤250mg/day) had higher risk of all-cause (HR: 1.56, 95% CI: 1.13-2.16) and other-cause (non-cardiovascular and non-cancer) mortality (HR: 1.68, 95% CI: 1.09-2.60), while cardiovascular and cancer-related mortality were similar compared with individuals with magnesium intake > 250mg/day. We also showed that the risk of all-cause (HR: 1.86, 95% CI: 1.33-2.60) and other-cause mortality (HR: 2.03, 95% CI: 1.29-3.19) were higher in individuals with poorly controlled diabetes (HbA1c ≥7.0%) compared with HbA1c 250mg/day). When combining HbA1c and dietary magnesium intake, we showed that individuals with HbA1c ≥ 7% and dietary magnesium intake ≤ 250 mg/day had higher all-cause and other-cause (non-cardiovascular and non-cancer) mortality risk compared with those with HbA1c 250 mg/day.
Conclusion
Higher magnesium intake may help reduce mortality risk in individuals with diabetes and attenuate mortality risk of poor diabetic control.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.