Lanzamiento Enero 2027

Metaanálisis2023

The Effect of Early Time-Restricted Eating vs Later Time-Restricted Eating on Weight Loss and Metabolic Health

Liu J, Yi P, Liu F

The Journal of clinical endocrinology and metabolism · 63 citas

Cómo se estudió

Diseño
Metaanálisis (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento

Quién lo pagó

Financiación
Financiación independiente
Gobierno
National Natural Science Foundation of China
Gobierno
National Key Research and Development Program of China
Subvenciones
National Key Research and Development Program of China (2019YFA0801900); National Natural Science Foundation of China (81730022); National Key Research and Development Program of China (2018YFC2000100)

Según 2 financiadores declarados.

Publicación

Publicado
2023-01-26 · J Clin Endocrinol Metab · vol. 108 · número 7 · págs. 1824–1834
Editorial
Oxford University Press
Citado
90 citas · más que el 99% de estudios similares · 12.3× el promedio de su campo
Impacto
Entre el 10 % más citado de su campo
Referencias
47 trabajos
Acceso
De pago
Áreas de investigación
Dietary Effects on Health · Circadian rhythm and melatonin · Enhanced Recovery After Surgery
Palabras clave
Overweight, Medicine, Glycemic, Weight loss, Insulin resistance, Context (archaeology), Cochrane Library, Randomized controlled trial, Internal medicine, Obesity, Blood pressure, Endocrinology, Eating behavior, Glucose homeostasis, Insulin, Biology
MeSH
humans, insulin resistance, obesity, body weight, weight loss, lipids, fasting, blood pressure, eating, adult, overweight

3 autores

  • Juanhong Liu🇨🇳Central South University; Second Xiangya Hospital of Central South University
  • Yi Pan🇨🇳Guangzhou Automobile Group (China)
  • Feng Liu🇨🇳 · autor de correspondenciaCentral South University; Second Xiangya Hospital of Central South University

Resumen

El texto original del estudio, en el idioma en que se publicó.

Context

It remains controversial whether the choice of the daily eating window early or later in time-restricted eating (TRE) intervention (early or later TRE) has different effects on weight loss and metabolic health.

Objective

A network meta-analysis was performed to evaluate the efficacy between early and later TRE in adults with obesity or overweight.

Methods

We searched PubMed, Embase, Web of Science, and Cochrane Library for randomized controlled trials (RCTs) published until October 16, 2022. We conducted a network meta-analysis to evaluate the efficacy of early and later TRE on body weight and metabolic parameters, including glycemic metabolism, blood pressure, and lipid profiles.

Results

Twelve RCTs with 730 obese or overweight adults were included in this meta-analysis. Early TRE and later TRE both elicited moderate reductions in body weight and insulin resistance (IR) (homeostasis model assessment of IR) when compared to non-TRE. Interestingly, early TRE showed more effectiveness than later TRE in improving IR (early vs later TRE: -0.44; 95% CI, -0.86 to -0.02; P .05). In addition, early TRE rather than later TRE showed significant benefits in glycemic metabolism and blood pressure when compared to non-TRE. No significant differences between early and later TRE were observed for fasting blood glucose, blood pressure, and lipid profiles.

Conclusion

This meta-analysis suggests that people may choose early TRE for more effective weight management and metabolic benefits. Nevertheless, further large-scale RCTs are warranted to verify our findings.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.

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