Creatine supplementation combined with blood flow restriction training enhances muscle thickness and performance: a randomized, placebo-controlled, and double-blind study
Sousa-Silva R, Cholewa JM, Pessôa KA, Xia Z, Lauver JD, Rossi FE, Zanchi NE
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 5 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Según 1 financiador declarado.
Publicación
- Publicado
- 2023-02-22 · Appl Physiol Nutr Metab · vol. 48 · número 6 · págs. 417–426
- Editorial
- NRC Research Press
- Citado
- 12 citas · más que el 79% de estudios similares · 1.4× el promedio de su campo
- Referencias
- 31 trabajos
- Acceso
- Acceso abierto (copia en repositorio)
- Áreas de investigación
- Muscle metabolism and nutrition · Sports Performance and Training · Cardiovascular and exercise physiology
- Palabras clave
- creatine supplementation, blood flow restriction training, resistance training, muscle hypertrophy, muscle thickness, muscle strength, muscular endurance, repetitions to failure, body composition, biceps curl, muscle adaptation
- MeSH
- muscle, skeletal, humans, creatine, double-blind method, regional blood flow, dietary supplements, male, muscle strength, resistance training, blood flow restriction therapy
7 autores
- Rayssa Sousa-Silva🇧🇷Universidade Federal do Maranhão
- Jason M. Cholewa🇺🇸University of Lynchburg
- Kassiana de Araújo Pessôa🇧🇷Universidade Federal do Maranhão
- Zhi Xia🇨🇳Jinggangshan University
- Jakob D. Lauver🇺🇸Coastal Carolina University
- Fabrício Eduardo Rossi🇧🇷Universidade Federal do Piauí
- Nelo Eidy Zanchi🇧🇷Universidade Federal do Maranhão
Resumen
El texto original del estudio, en el idioma en que se publicó.
This study aimed to compare the effects of an 8-week creatine (CR) or placebo (PL) supplementation on muscle strength, thickness, endurance, and body composition employing different training paradigms with blood flow restriction (BFR) vs. traditional resistance training (TRAD). Seventeen healthy males were randomized between the PL (n = 9) and CR (n = 8) groups. Participants were trained unilaterally utilizing a within-between subject bicep curl exercise where each arm was allocated to TRAD or BFR for 8 weeks. Muscular strength, thickness, endurance, and body composition were evaluated. Creatine supplementation promoted increases in muscle thickness in TRAD and BFR compared with their placebo counterparts, however, without a significant difference between treatments (p = 0.349). TRAD training increased maximum strength (1 repetition maximum (1RM)) compared with BFR after 8 weeks of training (p = 0.021). Repetitions to failure at 30% of 1RM were increased in the BFR-CR group compared with the TRAD-CR group (p = 0.004). Repetitions to failure at 70% 1RM were increased from weeks 0-4 (p p < 0.05) in all groups. Creatine supplementation exerted a hypertrophic effect when utilized with TRAD and BFR paradigms and increased muscle performance at 30% 1RM when utilized in conjunction with BFR. Therefore, creatine supplementation seems to amplify muscle adaptation following a BFR program. Registered in the Brazilian Registry of Clinical Trials (ReBEC), under the registration number: RBR-3vh8zgj.
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