Ultra-processed food consumption and increased risk of metabolic syndrome: a systematic review and meta-analysis of observational studies
Shu L, Zhang X, Zhou J, Zhu Q, Si C
Frontiers in nutrition · 18 citas
Cómo se estudió
- Diseño
- Revisión sistemática (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Natural Science Foundation of China
- Subvenciones
- National Natural Science Foundation of China (82004040)
Según 1 financiador declarado y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2023-06-09 · Front Nutr · vol. 10 · pág. 1211797
- Editorial
- Frontiers Media
- Citado
- 33 citas · más que el 88% de estudios similares · 2.1× el promedio de su campo
- Referencias
- 60 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Consumer Attitudes and Food Labeling · Nutritional Studies and Diet · Diet, Metabolism, and Disease
- Palabras clave
- ultra-processed foods, metabolic syndrome, NOVA classification, dietary intake, cardiovascular risk, study quality, subgroup analysis, sample size, publication bias, heterogeneity, dietary risk factors, cardiovascular risk factors, diabetes risk factors, obesity risk factors, hypertension risk factors, dyslipidemia risk factors, inflammatory markers, oxidative stress
5 autores
- Long Shu🇨🇳Zhejiang Hospital
- Xiaoyan Zhang🇨🇳Zhejiang Hospital
- Jianying Zhou🇨🇳Zhejiang Hospital
- Qin Zhu🇨🇳Zhejiang Hospital
- Caijuan Si🇨🇳 · autor de correspondenciaZhejiang Hospital
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Although higher consumption of ultra-processed food (UPF) has been linked to a higher risk of metabolic syndrome (MetS), the results remain controversial. Herein, we performed a systematic review and meta-analysis of observational studies to clarify the relationship between UPF consumption defined by the NOVA framework and risk of MetS.
Methods
An extensive literature search on PubMed, ISI Web of Science, EBSCO and China National Knowledge Infrastructure (CNKI) databases was conducted to search for the relevant articles published priori to January 2023, and newly published articles between January 2023 and March 2023 were re-searched. Random-effects or fixed-effects models were adopted to calculate the pooled relative risks (RRs) and 95% confidence intervals (CIs). The between-study heterogeneity was explored using the Cochran's Q test and I-square (I2). Publication bias was investigated using the visual inspection of asymmetry in funnel plots and Begg's and Egger's tests.
Results
Nine studies (six cross-sectional and three prospective cohort studies) totaling 23,500 participants with 6,192 MetS cases were included in the final analysis. The pooled effect size for the highest vs. lowest categories of UPF consumption indicated a positive association with the risk of MetS (RR: 1.25, 95%CI: 1.09-1.42, P P = 0.002), and no significant association in cohort studies (RR: 1.10, 95%CI: 0.96-1.27, P = 0.104), respectively. In addition, a more significant association between UPF consumption and increased risk of MetS was found in the subgroups of study quality P = 0.004) than study quality ≥7 (RR: 1.20; 95%CI: 1.06-1.36, P = 0.005). Similarly, when we performed analyses separately by sample size, there was a significant association between UPF consumption and MetS risk in sample size ≥5,000 (RR: 1.19; 95%CI: 1.11-1.27, P P = 0.013), respectively.
Conclusions
Our findings suggest that higher consumption of UPF is significantly associated with an increased risk of MetS. Further longitudinal studies are needed to confirm the effect of UPF consumption on MetS.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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