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Metaanálisis2023Acceso abierto

Time-restricted eating with calorie restriction on weight loss and cardiometabolic risk: a systematic review and meta-analysis

Sun JC, Tan ZT, He CJ, Hu HL, Zhai CL, Qian G

European journal of clinical nutrition · 35 citas

Cómo se estudió

Diseño
Metaanálisis (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento

Quién lo pagó

Financiación
Financiación independiente
Gobierno
National Natural Science Foundation of China
Gobierno
Natural Science Foundation of Zhejiang Province

Según 2 financiadores declarados y la declaración de financiación del texto completo.

Publicación

Publicado
2023-07-24 · Eur J Clin Nutr · vol. 77 · número 11 · págs. 1014–1025
Editorial
Springer Nature
Citado
43 citas · más que el 91% de estudios similares · 2.2× el promedio de su campo
Impacto
Entre el 10 % más citado de su campo
Referencias
59 trabajos
Acceso
Acceso abierto (revista híbrida) · CC-BY
Áreas de investigación
Dietary Effects on Health · Diet and metabolism studies · Circadian rhythm and melatonin
Palabras clave
Meta-analysis, Calorie, Calorie restriction, Medicine, Weight loss, Obesity, Body mass index, Systematic review, MEDLINE, Environmental health, Internal medicine, Biology
MeSH
humans, cardiovascular diseases, body weight, weight loss, caloric restriction, blood pressure

6 autores

  • Jing-Chao Sun🇨🇳Jiaxing University
  • Zhen-Tao Tan🇨🇳Zhejiang Chinese Medical University; Jiaxing University
  • Chao‐Jie He🇨🇳Jiaxing University
  • Huilin Hu🇨🇳Jiaxing University
  • Changlin Zhai🇨🇳Jiaxing University
  • Gang Qian🇨🇳 · autor de correspondenciaJiaxing University; First Hospital of Jiaxing

Resumen

El texto original del estudio, en el idioma en que se publicó.

The effect of time-restricted eating (TRE) has been summarized in previous studies, but its benefits in combination with calorie restriction (CR) still need to be determined. The present meta-analysis aimed to evaluate the efficacy of TRE with CR on weight loss and cardiometabolic risk. PubMed, Embase, Cochrane Library, and gray literature databases were searched from inception to October 18, 2022, for potential randomized controlled trial (RCT) studies based on predefined inclusion and exclusion criteria. Body weight and other cardiometabolic risk factors were described as weighted mean difference (WMD) with a 95% confidence interval (CI). Eight RCTs involving 579 participants were enrolled in the present analysis. The pooled results showed that TRE with CR reduced the body weight, fat mass, and waist circumference significantly (WMD: -1.40, 95% CI: -1.81 to -1.00, and I2: 0%; WMD: -0.73, 95% CI: -1.39 to -0.07, and I2: 0%; WMD: -1.87, 95% CI: -3.47 to -0.26, and I2: 67.25%, respectively). However, compared with CR alone, TRE plus CR exhibited no significant benefit on the blood pressure, glucose profile, and lipid profile. Subgroup analysis suggested that early TRE is more effective in weight loss (WMD: -1.42, 95% CI: -1.84 to -1.01, and I2: 0%) and improving fat mass (WMD: -1.06, 95% CI: -1.91 to -0.22, and I2: 0%) than delayed or broader TRE when combined with CR. Although the combination of TRE and CR can effectively decrease body weight, fat mass, and waist circumference, the long-term effects, particularly those on cardiometabolic risk in participants with chronic cardiovascular disease and diabetes, remain to be explored.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).

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