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Association between dietary magnesium intake and peripheral arterial disease: Results from NHANES 1999-2004

Wu Z, Ruan Z, Liang G, Wang X, Wu J, Wang B

PloS one · 22 citas

Cómo se estudió

Diseño
Estudio transversal (clasificado por nuestro filtro de IA)
Estudiado en
Personas
Resultado principal
Eventos clínicos como enfermedad o muerte

Quién lo pagó

Financiación
Financiación independiente

Según la declaración de financiación del texto completo.

Publicación

Publicado
2023-08-11 · PLoS One · vol. 18 · número 8 · pág. e0289973
Editorial
Public Library of Science
Citado
23 citas · más que el 91% de estudios similares · 2.8× el promedio de su campo
Impacto
Entre el 10 % más citado de su campo
Referencias
35 trabajos
Acceso
Acceso abierto (revista) · CC-BY
Áreas de investigación
Magnesium in Health and Disease · Parathyroid Disorders and Treatments · Peripheral Artery Disease Management
Palabras clave
Quartile, Medicine, Magnesium, National Health and Nutrition Examination Survey, Incidence (geometry), Magnesium deficiency (plants), Physiology, Dietary Reference Intake, Internal medicine, Nutrient, Endocrinology, Environmental health, Confidence interval, Population, Biology, Chemistry
MeSH
humans, magnesium, diet, nutrition surveys, risk factors, adult, aged, middle aged, united states, female, male, peripheral arterial disease

6 autores

  • Zhe Wu
  • Zhishen Ruan
  • Gang Liang
  • Xu Wang
  • Jianlin Wu🇨🇳 · autor de correspondenciaShandong University of Traditional Chinese Medicine
  • Bin Wang · autor de correspondencia

Resumen

El texto original del estudio, en el idioma en que se publicó.

Background

Magnesium has been found to have a strong association with peripheral arterial disease (PAD), and dietary magnesium intake shows promise as a predictor of the condition. However, the relationship between low dietary magnesium intake and an increased risk of PAD remains uncertain, and further research is needed to clarify this relationship.

Methods

This study analyzed data from 5969 participants in the National Health and Nutrition Examination Survey (NHANES) of the United States from 1999 to 2004. Multifactorial logistic regression models were used to investigate the association between dietary magnesium intake and PAD.

Results

Participants with PAD had lower dietary magnesium intake compared to those without PAD. After adjusting for all covariates, dietary magnesium intake remained negatively associated with PAD (OR: 0.999, 95% CI: 0.998, 1.000). When dietary magnesium intake was divided into quartiles, compared with the fourth quantile, the first quartile is associated with a higher incidence rate of PAD (OR: 1.560, 95%CI: 1.019, 2.386). Subgroup analysis revealed that the link between dietary magnesium intake and PAD remained significant among specific subgroups, including non-white, never or former smokers, and non-hypertensive, non-diabetic individuals (P < 0.05).

Conclusion

Our study provides evidence that dietary magnesium intake is negatively associated with the incidence of PAD. Therefore, people with inadequate dietary magnesium intake, particularly those with excessively low intake, should increase their magnesium intake to reduce the risk of PAD.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).

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