Association of ultra-processed foods consumption with risk of cardio-cerebrovascular disease: A systematic review and meta-analysis of cohort studies
Guo L, Li F, Tang G, Yang B, Yu N, Guo F, Li C
Nutrition, metabolism, and cardiovascular diseases : NMCD · 9 citas
Etiquetas de revisión
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Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2023-07-19 · Nutr Metab Cardiovasc Dis · vol. 33 · número 11 · págs. 2076–2088
- Editorial
- Elsevier BV
- Citado
- 19 citas · más que el 75% de estudios similares · 1.2× el promedio de su campo
- Referencias
- 71 trabajos
- Acceso
- Acceso abierto (revista híbrida) · CC-BY-NC-ND
- Áreas de investigación
- Consumer Attitudes and Food Labeling · Nutritional Studies and Diet · Cardiovascular Health and Risk Factors
- Palabras clave
- ultra-processed foods, cardio-cerebrovascular disease, cardiovascular disease, hypertension, diet and disease risk, dose-response relationship, dietary intake
- MeSH
- humans, cerebrovascular disorders, cardiovascular diseases, diet, risk assessment, risk factors, nutritive value, adult, aged, middle aged, female, male, fast foods, heart disease risk factors, food, processed
7 autores
- Lei Guo🇨🇳University of Electronic Science and Technology of China; Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
- Fumin Li🇨🇳University of Electronic Science and Technology of China; Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
- Guo Tang🇨🇳Sichuan University; West China Hospital of Sichuan University
- Bo Ram Yang🇨🇳University of Electronic Science and Technology of China; Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
- Nengwei Yu🇨🇳University of Electronic Science and Technology of China; Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
- Fuqiang Guo🇨🇳 · autor de correspondenciaUniversity of Electronic Science and Technology of China; Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
- Chunling Li🇨🇳 · autor de correspondenciaUniversity of Electronic Science and Technology of China; Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
Resumen
El texto original del estudio, en el idioma en que se publicó.
Aims
The epidemiological evidence regarding the impact of ultra-processed foods (UPFs) on the risk of cardio-cerebrovascular diseases (CCVDs) is controversial. The aim of this systematic review and meta-analysis is to examine the association between UPF consumption and the risk of CCVDs within cohort studies.
Data synthesis
A systematic literature search was conducted across multiple databases, including PubMed/Medline, Embase, Web of Science, Scopus, and the Cochrane Library databases, covering the inception of these databases up until January 1st, 2023. A total of 39 cohort studies involving 63,573,312 human participants were deemed eligible according to the inclusion criteria. Utilizing random-effects models, risk ratios (RRs) were estimated to determine the pooled results. Our findings indicate a significant association between a higher consumption of UPF and an increased likelihood of CCVDs (RR: 1.08, 95% CI: 1.01-1.16, I2 = 89%; p < 0.01) compared to individuals who either abstain from or consume lesser amounts of UPF. Nonlinear dose-response meta-analyses showed that a consistent high intake of UPFs was associated with an elevated risk of developing CCVDs (p non-linearity <0.001). Notably, the risk of CCVDs escalated by approximately 7% with an UPF intake of up to 1 serving per day. Subgroup analysis further revealed a significant augmentation in the risk of total CVD and hypertension with increased UPF consumption.
Conclusions
A higher intake of UPF significantly increases the risk of developing CCVDs. Prospective studies controlling for confounding factors are needed to validate the relationship between UPF intake and the development of CCVDs.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC-ND).
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