Association of Red Meat Intake and Colorectal Cancer among East-Asians: A Systematic Review and Meta-analysis of Observational Studies Performed between 2011-2021
Cheung HS, Lu LY, So WL, Wong HW, Wong SH, Mak CM
Journal of gastrointestinal and liver diseases : JGLD · 5 citas
Etiquetas de revisión
Financiación no declaradaMezcla carne procesada con no procesadaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2023-09-28 · J Gastrointestin Liver Dis · vol. 32 · número 3 · págs. 377–383
- Editorial
- Editura Medicală Universitară Iuliu Hatieganu
- Citado
- 7 citas · más que el 49% de estudios similares · 0.4× el promedio de su campo
- Referencias
- 38 trabajos
- Acceso
- Acceso abierto (publicación gratuita) · CC-BY-NC-ND
- Áreas de investigación
- Nutritional Studies and Diet · Meat and Animal Product Quality · Colorectal Cancer Screening and Detection
- Palabras clave
- Medicine, Funnel plot, Colorectal cancer, Publication bias, Red meat, Meta-analysis, Odds ratio, Incidence (geometry), Confidence interval, Internal medicine, Cohort study, Prospective cohort study, Cancer, Relative risk, Pathology
- MeSH
- humans, colorectal neoplasms, incidence, risk assessment, risk factors, observational studies as topic, red meat, asia, eastern, east asian people
6 autores
- Hoi Shan Cheung🇨🇳🇭🇰Duchess of Kent Children's Hospital; Hong Kong Children's Hospital
- Lok Yee Lu🇨🇳🇭🇰Duchess of Kent Children's Hospital; Hong Kong Children's Hospital
- Kevin Wang Leong So🇨🇳🇭🇰Duchess of Kent Children's Hospital; Hong Kong Children's Hospital
- Ho Wai Wong🇨🇳🇭🇰Duchess of Kent Children's Hospital; Hong Kong Children's Hospital
- Sei Hei Wong🇨🇳🇭🇰Duchess of Kent Children's Hospital; Hong Kong Children's Hospital
- Chloe Miu Mak🇨🇳🇭🇰Duchess of Kent Children's Hospital; Hong Kong Children's Hospital
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background and aims
Colorectal cancer has the third highest incidence and second highest mortality among all cancers worldwide. Although numerous studies investigating the associations between high red meat intake and risk of colorectal cancer have been published, the association between the intake of red meat and the risk of colorectal cancer in Asians remains unclear. We performed a systematic review and meta-analysis of cohort and case-control studies to estimate the association between red meat intake and colorectal cancer incidence rate between 2011-2021.
Method
We searched PubMed database from 1 Jan 2011 to 21 July 2021. Prospective cohort studies and nested case-control studies that reported results on the association between red meat consumption and colorectal cancer were included in the meta-analysis. The outcome of interest was the association between the intake of red meat and the risk of colorectal cancer. We performed a meta-analysis to calculate the odds ratios (OR) with 95% confidence intervals (CI).
Results
A total of 5 studies enrolling 48,158 participants were included. The results showed no significant association between red meat intake and colorectal cancer risks (OR=1.38; 95%CI: 0.98-1.93). The aspect of the corresponding funnel plot suggested the presence of significant publication bias. Egger's test confirmed the significant asymmetry of the funnel plot (t = 9.3024, p = 0.0026).
Conclusions
Contrary to many other meta-analyses, our study showed that intake of red meat was not associated with increased risk of colorectal cancer in East-Asians from China, Japan and South Korea. However, due to the limited number of included papers and the lack of confounders adjustments, our results warrant cautious interpretations.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC-ND).
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