Nonlinear relationship between dietary calcium and magnesium intake and peripheral neuropathy in the general population of the United States
Wu Z, Yang X, Ruan Z, Li L, Wu J, Wang B
Frontiers in nutrition · 5 citas
Cómo se estudió
- Diseño
- Estudio transversal (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
Quién lo pagó
- Financiación
- Financiación independiente
Según la declaración de financiación del texto completo.
Publicación
- Publicado
- 2023-09-18 · Front Nutr · vol. 10 · pág. 1217465
- Editorial
- Frontiers Media
- Citado
- 5 citas · más que el 64% de estudios similares · 0.6× el promedio de su campo
- Referencias
- 33 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Magnesium in Health and Disease · Pain Mechanisms and Treatments · Trace Elements in Health
- Palabras clave
- Medicine, Peripheral neuropathy, Calcium, Magnesium, Internal medicine, Quantile, Peripheral, Endocrinology, Incidence (geometry), Quantile regression, National Health and Nutrition Examination Survey, Population, Diabetes mellitus, Chemistry, Environmental health
6 autores
- Zhe Wu🇨🇳Shandong University of Traditional Chinese Medicine; Affiliated Hospital of Liaoning University of Traditional Chinese Medicine
- Xuesong Yang🇨🇳Affiliated Hospital of Shandong University of Traditional Chinese Medicine
- Zhishen Ruan🇨🇳Shandong University of Traditional Chinese Medicine; Affiliated Hospital of Liaoning University of Traditional Chinese Medicine
- Lianlian Li🇨🇳Shandong University of Traditional Chinese Medicine; Affiliated Hospital of Liaoning University of Traditional Chinese Medicine
- Jianlin Wu🇨🇳 · autor de correspondenciaShandong University of Traditional Chinese Medicine
- Bin Wang🇨🇳 · autor de correspondenciaShandong University of Traditional Chinese Medicine; Affiliated Hospital of Liaoning University of Traditional Chinese Medicine; Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Calcium and magnesium are essential minerals that have significant roles in nerve function and regulation. There may be a correlation between dietary calcium and magnesium intake and peripheral neuropathy. However, this relationship remains unclear and requires further study.
Methods
Data from 7,726 participants in the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2004 were analyzed in this study. The relationship between total dietary calcium and magnesium intake, as well as each quantile, and peripheral neuropathy was analyzed using a multifactor logistic regression model. To illustrate the dose-response relationship between calcium and magnesium intake and peripheral neuropathy, we utilized a restricted cubic spline (RCS) plot.
Results
Our analysis found a positive correlation between dietary intake of calcium and magnesium and peripheral neuropathy (calcium: OR 1.000, 95% CI 1.000-1.000; magnesium: OR 1.001, 95% CI 1.00-1.002). Participants in the first and third quantiles of dietary calcium intake had a significantly higher incidence of peripheral neuropathy than those in the second quantile (OR 1.333, 95% CI 1.034-1.719, OR 1.497, 95% CI 1.155-1.941). Those in the first and third quantiles of dietary magnesium intake also had a significantly higher incidence of peripheral neuropathy than those in the second quantile (OR 1.275, 95% CI 1.064-1.528, OR 1.525, 95% CI 1.231-1.890). The restricted cubic spline analysis revealed a U-shaped nonlinear relationship between dietary intake of calcium and magnesium and peripheral neuropathy.
Conclusion
The study found a U-shaped non-linear relationship between dietary calcium and magnesium intake levels and peripheral neuropathy, indicating that both excessive and insufficient intake of calcium and magnesium can increase the incidence of peripheral neuropathy.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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