Effects of low-level laser therapy on burning pain and quality of life in patients with burning mouth syndrome: a systematic review and meta-analysis
Lu C, Yang C, Li X, Du G, Zhou X, Luo W, Du Q, Tang G
BMC oral health · 21 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Innovative Research Team of High-level Local University in Shanghai
- Universidad u hospital
- Innovative research team of high-level local universities in Shanghai
- Subvenciones
- Innovative Research Team of High-level Local University in Shanghai (SHSMU‐ZLCX20212401)
Según 2 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2023-10-09 · BMC Oral Health · vol. 23 · número 1 · pág. 734
- Editorial
- BioMed Central
- Citado
- 30 citas · más que el 88% de estudios similares · 1.7× el promedio de su campo
- Referencias
- 71 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Laser Applications in Dentistry and Medicine · Oral Health Pathology and Treatment · Oral health in cancer treatment
- Palabras clave
- burning mouth syndrome, low-level laser therapy, burning pain, quality of life, anxiety, depression, clonazepam, chronic pain, oral health-related quality of life
- MeSH
- humans, burning mouth syndrome, quality of life, chronic pain, low-level light therapy
8 autores
- Chenghui Lu🇨🇳Guilin Medical University
- Chenglong Yang🇨🇳Shanghai Jiao Tong University; XinHua Hospital
- Xin Li🇨🇳Shanghai Jiao Tong University; XinHua Hospital
- Guanhuan Du🇨🇳Shanghai Jiao Tong University; Shanghai Ninth People's Hospital
- Xuan Zhou🇨🇳Shanghai Jiao Tong University; XinHua Hospital
- Wenhai Luo🇨🇳Guilin Medical University
- Qing Du🇨🇳 · autor de correspondenciaShanghai Jiao Tong University; XinHua Hospital
- Guoyao Tang🇨🇳 · autor de correspondenciaShanghai Jiao Tong University; XinHua Hospital
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Burning mouth syndrome (BMS) is a complex chronic pain disorder that significantly impairs patients' quality of life. Low-level laser therapy (LLLT) uses infrared or near-infrared light to produce analgesic, anti-inflammatory, and biological stimulation effects. The aim of this systematic review is to evaluate the effect of LLLT on burning pain, quality of life, and negative emotions in patients with BMS.
Methods
The PubMed, Embase, Cumulative Index of Nursing and Allied Health Literature (CINAHL), Cochrane Library, Web of Science, and Scopus databases were searched up January 2023 to identify relevant articles. All randomized controlled trials that were published in English and examined the use of LLLT treatment for BMS were included. The methodological quality of the included trials was assessed using the Cochrane risk of bias tool for randomized controlled trials (RCTs). A meta-analysis was performed to evaluate burning pain, quality of life, and negative emotions. Sensitivity, subgroup, and funnel plot analyses were also carried out.
Results
Fourteen RCTs involving a total of 550 patients with BMS met the inclusion criteria. The results showed that LLLT (measured by the Visual Analog Scale; SMD: -0.87, 95% CI: -1.29 to -0.45, P < 0.001) was more effective for reducing burning pain than placebo LLLT or clonazepam. LLLT improved quality of life (evaluated by the Oral Health Impact Profile-14; SMD: 0.01, 95% CI: -0.58 to 0.60, P = 0.97) and negative emotions (evaluated by the Hospital Anxiety and Depression Scale; SMD: -0.12, 95% CI: -0.54 to 0.30, P = 0.59), but these effects were not statistically significant.
Conclusions
The meta-analysis revealed that LLLT may be an effective therapy for improving burning pain in patients with BMS, and producing a positive influence on quality of life and negative emotions. A long-term course of intervention, a larger sample size, and a multidisciplinary intervention design are urgently needed in future research.
Trial registration
PROSPERO registration number: CRD42022308770.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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