Efficacy of Time-Restricted Eating and Behavioral Economic Intervention in Reducing Fasting Plasma Glucose, HbA1c, and Cardiometabolic Risk Factors in Patients with Impaired Fasting Glucose: A Randomized Controlled Trial
Suthutvoravut U, Anothaisintawee T, Boonmanunt S, Pramyothin S, Siriyothin S, Attia J, McKay GJ, Reutrakul S, Thakkinstian A
Nutrients · 19 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Research Council of Thailand
- Gobierno
- National Institute of Diabetes and Digestive and Kidney Diseases
- Gobierno
- NIDDK NIH HHS
- Subvenciones
- National Institute of Diabetes and Digestive and Kidney Diseases (P30DK020595); National Research Council of Thailand (186/2564)
Según 3 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2023-09-30 · Nutrients · vol. 15 · número 19 · pág. 4233
- Editorial
- Multidisciplinary Digital Publishing Institute
- Citado
- 24 citas · más que el 94% de estudios similares · 3.5× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 43 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Dietary Effects on Health · Diabetes, Cardiovascular Risks, and Lipoproteins · Diabetes Management and Research
- Palabras clave
- time-restricted eating, behavioral economics, impaired fasting glucose, fasting blood glucose, HbA1c, fasting insulin, cardiometabolic risk factors, prediabetes, dietary adherence, lipid profile, body weight
- MeSH
- humans, pancreatic diseases, prediabetic state, body weight, insulin, blood glucose, lipids, fasting, adolescent, adult, aged, middle aged, young adult, economics, behavioral, cardiometabolic risk factors, glycated hemoglobin
9 autores
- Unyaporn Suthutvoravut🇹🇭Mahidol University; Ramathibodi Hospital
- Thunyarat Anothaisintawee🇹🇭 · autor de correspondenciaMahidol University; Ramathibodi Hospital
- Suparee Wisawapipat Boonmanunt🇹🇭Mahidol University; Ramathibodi Hospital
- Sarunporn Pramyothin🇹🇭Mahidol University; Ramathibodi Hospital
- Sukanya Siriyothin🇹🇭Mahidol University; Ramathibodi Hospital
- John Attia🇦🇺University of Newcastle Australia
- Gareth J. McKay🇬🇧Queen's University Belfast
- Sirimon Reutrakul🇺🇸University of Illinois Chicago
- Ammarin Thakkinstian🇹🇭Mahidol University; Ramathibodi Hospital
Resumen
El texto original del estudio, en el idioma en que se publicó.
This randomized controlled trial is aimed at assessing the efficacy of combining time-restricted eating (TRE) with behavioral economic (BE) interventions and comparing it to TRE alone and to the usual care for reducing fasting plasma glucose (FPG), hemoglobin A1c (HbA1c), and other cardiometabolic risk factors among patients with impaired fasting glucose (IFG). Seventy-two IFG patients aged 18-65 years were randomly allocated for TRE with BE interventions (26 patients), TRE alone (24 patients), or usual care (22 patients). Mean FPG, HbA1c, and other cardiometabolic risk factors among the three groups were compared using a mixed-effect linear regression analysis. Mean body weight, FPG, HbA1c, fasting insulin, and lipid profiles did not significantly differ among the three groups. When considering only patients who were able to comply with the TRE protocol, the TRE group showed significantly lower mean FPG, HbA1c, and fasting insulin levels compared to the usual care group. Our results did not show significant differences in body weight, blood sugar, fasting insulin, or lipid profiles between TRE plus BE interventions, TRE alone, and usual care groups. However, TRE might be an effective intervention in lowering blood sugar levels for IFG patients who were able to adhere to the TRE protocol.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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