The optimal time restricted eating interventions for blood pressure, weight, fat mass, glucose, and lipids: A meta-analysis and systematic review
Liang X, Chen J, An X, Ren Y, Liu Q, Huang L, Zhang P, Qu P, Li J
Trends in cardiovascular medicine · 16 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Chongqing Municipal Health Commission
- Gobierno
- National Natural Science Foundation of China
- Gobierno
- Ministry of Education of the People's Republic of China
- Gobierno
- Chongqing Science and Technology Commission
- Universidad u hospital
- Chongqing Medical University
- Gobierno
- National Key Research and Development Program of China
- Gobierno
- Ministry of Education of the People's Republic of China
- Gobierno
- Chongqing Municipal Science and Technology Bureau
- Subvenciones
- Chongqing Science and Technology Commission (CSTC2021jscx-gksb-N0001); Chongqing Municipal Health Commission (2020MSXM062); Ministry of Education of the People's Republic of China (GBRP-202106); National Key Research and Development Program of China (ZHYX202109); National Natural Science Foundation of China (82373590); National Key Research and Development Program of China (2017YFC0211705); Chongqing Medical University (W0088)
Según 8 financiadores declarados.
Publicación
- Publicado
- 2023-10-12 · Trends Cardiovasc Med · vol. 34 · número 6 · págs. 389–401
- Editorial
- Elsevier BV
- Citado
- 18 citas · más que el 69% de estudios similares · 0.9× el promedio de su campo
- Referencias
- 79 trabajos
- Acceso
- De pago
- Áreas de investigación
- Dietary Effects on Health · Nutritional Studies and Diet · Diet and metabolism studies
- Palabras clave
- time-restricted eating, cardiovascular risk factors, blood pressure, body weight, fat mass, blood glucose, lipids, obesity, meal timing
- MeSH
- humans, cardiovascular diseases, weight loss, blood glucose, lipids, treatment outcome, risk assessment, risk reduction behavior, blood pressure, time factors, adult, aged, middle aged, female, male, adiposity, protective factors, biomarkers, heart disease risk factors, intermittent fasting
9 autores
- Xiaohua Liang🇨🇳 · autor de correspondenciaChildren's Hospital of Chongqing Medical University; Chongqing Medical University
- Jingyu Chen🇨🇳Children's Hospital of Chongqing Medical University; Chongqing Medical University
- Xizou An🇨🇳Children's Hospital of Chongqing Medical University; Chongqing Medical University
- Yanling Ren🇨🇳Children's Hospital of Chongqing Medical University; Chongqing Medical University
- Qin Liu🇨🇳Children's Hospital of Chongqing Medical University; Chongqing Medical University
- Lan Huang🇨🇳Children's Hospital of Chongqing Medical University; Chongqing Medical University
- Ping Zhang🇨🇳Children's Hospital of Chongqing Medical University; Chongqing Medical University
- Ping Qü🇨🇳Children's Hospital of Chongqing Medical University; Chongqing Medical University
- Jianxin Li🇨🇳Chinese Academy of Medical Sciences & Peking Union Medical College; Fu Wai Hospital
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
No previous systematic review or meta-analysis has evaluated the effect of optimal time-restricted eating (TRE) interventions on cardiovascular (CVD) risk factors. This meta-analysis aimed to illustrate the effect of a suitable TRE on CVD risk factors.
Methods
A systematic review was performed to identify trials reporting the effects of TRE, relative to non-diet controls, on CVD risk factors in humans. A random-effects model was used to evaluate the effect sizes, and the results are expressed as the mean difference (MD) and 95% confidence intervals (CIs). Subgroup analyses were performed to examine the influence of the study population, age, duration of intervention, and baseline mean BMI on the CVD indexes.
Results
TRE intervention significantly reduced systolic pressure (SBP) (MD: -3.45 mmHg; 95%CI:(-6.20,-0.71) mmHg; P = 0.01), body weight (MD: -1.63 Kg; 95%CI:(-2.09,-1.17) Kg; P2; 95% CI: (-0.72, -0.22) Kg/m2; P<0.001), and fat mass (MD: -0.98 Kg; 95% CI: (-1.51,-0.44) Kg; P<0.001), and reduced blood glucose levels. Based on the results of subgroup analysis, this meta-analysis identified the optimal TRE for BP (with a 6 h feeding window, last eating time point at 6-8 PM, and male participants with obesity and aged ≥ 45 years), obesity (with a 6 h feeding window, last eating time point at 6-8 PM, and female participants aged ≥ 45 years), lipids (with an 8 h feeding window, last eating time point at 6-8 PM, and male participants aged < 45 years), and glucose (with a 10-12 h feeding window, last eating time point before 6 PM, and female participants aged < 45years).
Conclusions
Relative to a non-diet control, TRE is effective for the improvement of CVD risks. Moreover, individual TRE interventions should be developed for different populations to achieve the most effective health improvement for CVD risk factors.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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