Magnesium intake and all-cause mortality after stroke: a cohort study
Wang M, Peng J, Yang C, Zhang W, Cheng Z, Zheng H
Nutrition journal · 18 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Estudio de cohortes (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2023-10-30 · Nutr J · vol. 22 · número 1 · pág. 54
- Editorial
- BioMed Central
- Citado
- 17 citas · más que el 87% de estudios similares · 2.1× el promedio de su campo
- Referencias
- 28 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Magnesium in Health and Disease · Parathyroid Disorders and Treatments · Potassium and Related Disorders
- Palabras clave
- Medicine, Quartile, Stroke (engine), National Health and Nutrition Examination Survey, Confounding, Magnesium, Proportional hazards model, Clinical nutrition, Cohort, Internal medicine, Population, Cohort study, Environmental health, Confidence interval
- MeSH
- humans, cardiovascular diseases, magnesium, nutrition surveys, cohort studies, female, male, stroke
6 autores
- Mengyan Wang🇨🇳Taizhou First People's Hospital
- Jianhong Peng🇨🇳Taizhou First People's Hospital
- Caili Yang🇨🇳Taizhou First People's Hospital
- Wenyuan Zhang🇨🇳Wenzhou Medical University
- Zicheng Cheng🇨🇳 · autor de correspondenciaJinhua Central Hospital
- Haibin Zheng🇨🇳 · autor de correspondenciaWenzhou Medical University; Taizhou First People's Hospital; Zhejiang Taizhou Hospital
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Population-based studies have shown that adequate magnesium intake is associated with a lower risk of stroke and all-cause mortality. Whether adequate magnesium intake is important for reducing all-cause mortality risk after stroke remains unclear.
Methods
We analyzed data from 917 patients with a self-reported history of stroke from the National Health and Nutrition Examination Survey (NHANES) 2007-2018. The total magnesium intake was calculated by summing the magnesium intake from dietary and dietary supplements, and then adjusting for total energy intake according to the nutrient density method. Mortality status was determined using public-use linked mortality files from 2019. Cox regression model and restricted cubic splines were used to explore the relationship between magnesium intake and all-cause mortality.
Results
The average total magnesium intake across all patients was 251.0 (184.5-336.5) mg/d, and 321 (70.2%) males and 339 (73.7%) females had insufficient magnesium intake. During a median follow-up period of 5.3 years, 277 deaths occurred. After fully adjusting for confounding factors, total magnesium intake levels were inversely associated with all-cause mortality risk (HR per 1-mg/(100 kcal*d) increase, 0.97; 95% CI, 0.94-1.00; p = 0.017). Participants with the highest quartile of total magnesium intake (≥ 18.5 mg/(100 kcal*d)) had a 40% reduction in all-cause mortality risk compared to those with the lowest quartile (≤ 12.0 mg/(100 kcal*d)) (HR, 0.60; 95% CI, 0.38-0.94; p = 0.024). Stratified analyses showed that this inverse association was statistically significant in those who were older, female, without hypertension, and had smoking, normal renal function, and adequate energy intake. Dietary magnesium intake alone might be not related to all-cause mortality.
Conclusions
Stroke survivors who consumed adequate amounts of magnesium from diet and supplements had a lower risk of all-cause mortality.
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