Association of Whole Grain Consumption and Cognitive Decline: An Investigation From a Community-Based Biracial Cohort of Older Adults
Liu X, Beck T, Dhana K, Desai P, Krueger KR, Tangney CC, Holland TM, Agarwal P, Evans DA, Rajan KB
Neurology · 15 citas
Etiquetas de revisión
Cuestionario de frecuencia de consumoSin ajuste declarado por estilo de vidaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Estudio de cohortes (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- Cuestionario de frecuencia de consumo
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Institutes of Health
- Gobierno
- National Institute on Aging
- Gobierno
- NIA NIH HHS
- Subvenciones
- National Institute on Aging (R01 AG058679); National Institute on Aging (R01AG073627)
Según 3 financiadores declarados.
Publicación
- Publicado
- 2023-11-21 · Neurology · vol. 101 · número 22 · págs. e2277–e2287
- Editorial
- Lippincott Williams & Wilkins
- Citado
- 17 citas · más que el 94% de estudios similares · 3.9× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 55 trabajos
- Acceso
- Acceso abierto (copia en repositorio)
- Áreas de investigación
- Nutritional Studies and Diet · Obesity, Physical Activity, Diet · Consumer Attitudes and Food Labeling
- Palabras clave
- Cognition, Episodic memory, Cognitive decline, Demography, Ethnic group, Whole grains, Medicine, Association (psychology), Effects of sleep deprivation on cognitive performance, Gerontology, Psychology, Internal medicine, Psychiatry, Food science
- MeSH
- humans, diet, cognition, aging, aged, female, male, whole grains, cognitive dysfunction
10 autores
- Xiaoran Liu🇺🇸Rush University Medical Center
- Todd L. Beck🇺🇸Rush University Medical Center
- Klodian Dhana🇺🇸Rush University Medical Center
- Pankaja M Desai🇺🇸Rush University Medical Center
- Kristin R. Krueger🇺🇸Rush University Medical Center
- Christy Tangney🇺🇸Rush University Medical Center
- Thomas Monroe Holland🇺🇸Rush University Medical Center
- Puja Agarwal🇺🇸Rush University Medical Center
- Denis A. Evans🇺🇸Rush University Medical Center
- Kumar Bharat Rajan🇺🇸Rush University Medical Center
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background and objectives
To examine the association of whole grain consumption and longitudinal change in global cognition, perceptual speed, and episodic memory by different race/ethnicity.
Methods
We included 3,326 participants from the Chicago Health and Aging Project who responded to a Food Frequency Questionnaire (FFQ), with 2 or more cognitive assessments. Global cognition was assessed using a composite score of episodic memory, perceptual speed, and the Mini Mental State Examination (MMSE). Diet was assessed by a 144-item FFQ. Linear mixed-effects models were used to estimate the association of intakes of whole grains and cognitive decline.
Results
This study involved 3,326 participants (60.1% African American [AA], 63.7% female) with a mean age of 75 years at baseline and a mean follow-up of 6.1 years. Higher consumption of whole grains was associated with a slower rate of global cognitive decline. Among AA participants, those in the highest quintile of whole grain consumption had a slower rate of decline in global cognition (β = 0.024, 95% CI [0.008-0.039], p = 0.004), perceptual speed (β = 0.023, 95% CI [0.007-0.040], p = 0.005), and episodic memory (β = 0.028, 95% CI [0.005-0.050], p = 0.01) compared with those on the lowest quintile. Regarding the amount consumed, in AA participants, those who consumed >3 servings/d vs those who consumed p = 0.0093). In White participants, with >3 servings/d, we found a suggestive association of whole grains with global cognitive decline when compared with those who consumed p = 0.08).
Discussion
Among AA participants, individuals with higher consumption of whole grains and more frequent consumption of whole grain had slower decline in global cognition, perceptual speed, and episodic memory. We did not see a similar trend in White adults.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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