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Dietary Magnesium Intake and Kidney Stone: The National Health and Nutrition Examination Survey 2011-2018

Shringi S, Raker CA, Tang J

Rhode Island medical journal (2013) · 7 citas

Etiquetas de revisión

Financiación no declarada

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Cómo se estudió

Diseño
Estudio transversal (clasificado por nuestro filtro de IA)
Estudiado en
Personas
Resultado principal
Eventos clínicos como enfermedad o muerte

Quién lo pagó

Financiación
Financiación no declarada

Publicación

Publicado
2023-12-01 · R I Med J (2013) · vol. 106 · número 11 · págs. 20–25
Editorial
National Institutes of Health
Citado
6 citas · más que el 77% de estudios similares · 1.0× el promedio de su campo
Referencias
0 trabajos
Acceso
De pago
Áreas de investigación
Kidney Stones and Urolithiasis Treatments · Magnesium in Health and Disease · Parathyroid Disorders and Treatments
Palabras clave
National Health and Nutrition Examination Survey, Medicine, Quartile, Odds ratio, Logistic regression, Kidney disease, Internal medicine, Diabetes mellitus, Univariate analysis, Environmental health, Endocrinology, Confidence interval, Multivariate analysis, Population
MeSH
humans, kidney calculi, magnesium, diet, nutrition surveys, regression analysis

3 autores

  • Sandipan Shringi🇺🇸Brown University
  • Christina Raker🇺🇸Brown University
  • Jie Tang🇺🇸Brown University

Resumen

El texto original del estudio, en el idioma en que se publicó.

Background

The association between dietary magnesium intake (DMI) and kidney stone (KS) disease is not clear.

Aim

To determine the association between DMI and prevalent KS disease defined as self-report of any previous episode of KS.

Methods

We examined The National Health and Nutrition Examination Survey (NHANES) 2011-2018 and used logistic regression analyses adjusting for demographics, BMI, histories of hypertension, diabetes, thiazide use, cigarette smoking, alcohol drinking, relevant dietary and supplemental intakes to determine the independent association between DMI and prevalent KS disease.

Results

A total of 19,271 participants were eligible for the final analysis, including 1878 prevalent KS formers. Mean DMI among stone formers was 295.4 mg/day, as compared to 309.6 mg/day among non-stone formers (p=0.02). Higher DMI was strongly associated with lower odds of prevalent KS disease in univariate analysis regardless of when DMI was analyzed as a continuous variable (OR=0.94, 95% CI: 0.89-0.99, p=0.02) or when the extreme quartiles of DMI were compared (OR=0.74, 95% CI: 0.60-0.92, p=0.007). In the multivariable-adjusted regression analysis, those in the highest quartile of DMI compared to the lowest quartile (≥379 mg vs. <205 mg) had significantly reduced odds of prevalent KS (OR=0.70, 95% CI: 0.52-0.93, p=0.01). When DMI was analyzed as a continuous variable, there was a trend toward reduced odds of prevalent KS disease with higher DMI (OR=0.92 per 100 mg, 95% CI: 0.84-1.01, p=0.07).

Conclusions

Our study suggests that higher DMI is associated with a reduced risk of KS disease. Future prospective studies are needed to clarify the causal relationship between DMI and KS disease.

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