Dietary Magnesium Intake and Proteinuria: Is There a Relationship?
Mohtashamian A, Mozaffari-Rad N, Soleimani A, Akbari H, Arabi V, Sharifi N
Biological trace element research · 2 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Kashan University of Medical Sciences
- Subvenciones
- Kashan University of Medical Sciences (97102)
Según 1 financiador declarado.
Publicación
- Publicado
- 2023-12-19 · Biol Trace Elem Res · vol. 202 · número 9 · págs. 3959–3966
- Editorial
- Springer Science+Business Media
- Citado
- 2 citas · más que el 58% de estudios similares · 0.3× el promedio de su campo
- Referencias
- 48 trabajos
- Acceso
- De pago
- Áreas de investigación
- Magnesium in Health and Disease · Nutritional Studies and Diet · Dialysis and Renal Disease Management
- Palabras clave
- dietary magnesium, proteinuria, urine protein-to-creatinine ratio, chronic kidney disease, phosphate limitation, magnesium supplementation, trace elements
- MeSH
- humans, proteinuria, magnesium, creatinine, diet, adult, aged, middle aged, female, male
6 autores
- Abbas Mohtashamian🇮🇷Kashan University of Medical Sciences
- Negar Mozaffari-Rad🇮🇷Kashan University of Medical Sciences
- Alireza Soleimani🇮🇷Kashan University of Medical Sciences
- Hossein Akbari🇮🇷Kashan University of Medical Sciences
- Vahid Arabi🇮🇷Shahid Sadoughi University of Medical Sciences and Health Services
- Nasrin Sharifi🇮🇷 · autor de correspondenciaKashan University of Medical Sciences
Resumen
El texto original del estudio, en el idioma en que se publicó.
The possible relationship between dietary magnesium status and proteinuria has been suggested by a number of previous studies. However, human studies on this association are limited. Therefore, the present study aimed to investigate the independent relationship between dietary magnesium intake and urinary protein excretion. The present study was a post hoc analysis of the previous randomized clinical trial that evaluated the effect of dietary phosphorus restriction on proteinuria. The baseline data of 90 participants with proteinuria and chronic kidney disease was used to measure the association between dietary magnesium intake and proteinuria. Participants were asked to record their 24-h food intake for three days a week in a questionnaire. Urinary protein to creatinine ratio (UPCR) in a random urine sample was measured to be a marker for proteinuria. Out of 90 patients included in the study, 47 were men and 43 were women. The mean ± standard deviation of age and body mass index were 59.05 ± 14.16 years and 29.02 ± 5.54 kg/m2, respectively. The patients' average daily dietary intake of energy and magnesium were 2183 kcal and 169.44 mg, respectively. A significant inverse correlation was found between the dietary intake of magnesium and UPCR (r = - 0.219, p = 0.042). This association remained significant even after adjusting for confounding variables (β = - 0.222, p = 0.028). The findings of the present study showed a significant inverse relationship between the magnesium intake and proteinuria. Although, the design of the current research was cross-sectional, it has provided a basis for conducting future longitudinal studies and trials to better elucidate such a relationship.
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