Effects of repeated low-level red-light therapy on macular retinal thickness and microvascular system in children with myopia
Liu L, Wang Y, Liu F, Yu X, Xie L, Tan S, Liu J, Liu Y, Huang J, Zhang S, Jiang Y
Photodiagnosis and photodynamic therapy · 16 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Estudio de cohortes (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2024-01-18 · Photodiagnosis Photodyn Ther · vol. 45 · pág. 103938
- Editorial
- Elsevier BV
- Citado
- 21 citas · más que el 97% de estudios similares · 5.5× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 26 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY-NC-ND
- Áreas de investigación
- Ophthalmology and Visual Impairment Studies · Retinal Diseases and Treatments · Retinopathy of Prematurity Studies
- Palabras clave
- Retinal, Medicine, Ophthalmology, Visual acuity, Optical coherence tomography, Significant difference, Internal medicine
- MeSH
- retinal vessels, retina, humans, myopia, photosensitizing agents, photochemotherapy, prospective studies, child, low-level light therapy
11 autores
- Linlin Liu🇨🇳Gannan Medical University; First Affiliated Hospital of Gannan Medical University
- Yuchuan Wang🇨🇳Gannan Medical University; The People's Hospital of LinXia; First Affiliated Hospital of Gannan Medical University
- Fang Liu🇨🇳Gannan Medical University; First Affiliated Hospital of Gannan Medical University
- Xing-Hui Yu🇨🇳Gannan Medical University; First Affiliated Hospital of Gannan Medical University
- Lian-Feng Xie🇨🇳Gannan Medical University; First Affiliated Hospital of Gannan Medical University
- Shuxiang Tan🇨🇳Gannan Medical University; First Affiliated Hospital of Gannan Medical University
- Jing Liu🇨🇳Gannan Medical University; First Affiliated Hospital of Gannan Medical University
- Yanfang Liu🇨🇳Gannan Medical University; First Affiliated Hospital of Gannan Medical University
- Jiaxing Huang🇨🇳Gannan Medical University; First Affiliated Hospital of Gannan Medical University
- Shuang Zhang🇨🇳Gannan Medical University; First Affiliated Hospital of Gannan Medical University
- Yi-Ping Jiang🇨🇳 · autor de correspondenciaGannan Medical University; First Affiliated Hospital of Gannan Medical University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objective
The objective of the study was to use optical coherence tomography angiography (OCTA) to analyze the effects of repeated low-level red-light (LLLT) therapy on macular retinal thickness and the microvascular system in children with myopia to evaluate the safety of this therapy.
Methods
This prospective study included 40 school-age children with myopia (80 eyes), aged 7-14 years, who received therapy using a LLLT instrument. At baseline and therapy for 1 month, 3 months, 6 months, all children underwent comprehensive ophthalmological examinations, including slit-lamp examination, uncorrected visual acuity, best-corrected visual acuity, spherical equivalent degree, axial length, and OCTA. The vessel densities of the superficial retinal capillary plexus, macular inner retinal thickness, and full-layer retinal thickness were measured.
Results
The macular inner retinal thickness increased at 1 month and remained unchanged thereafter, It differed significantly in nine areas at 1, 3, and 6 months compared to the thicknesses before therapy (P 0.05). The macular full-layer retinal thickness increased at 1 month and remained unchanged thereafter; the changes showed significant differences at 1 month and 3 months compared to before therapy, for the inner nasal region (P 0.05). The vessel density of the superficial retinal capillary plexus did not differ significantly among the four groups (P > 0.05).
Conclusions
LLLT therapy was safe. The school-aged children exhibited macular thickening after LLLT therapy, which had no significant effect on macular microcirculation.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC-ND).
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