Effectiveness of an intermittent fasting diet versus regular diet on fat loss in overweight and obese middle-aged and elderly people without metabolic disease: a systematic review and meta-analysis of randomized controlled trials
Yao K, Su H, Cui K, Gao Y, Xu D, Wang Q, Ha Z, Zhang T, Chen S, Liu T
The journal of nutrition, health & aging · 20 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Key Research and Development Program of China
- Subvenciones
- National Key Research and Development Program of China (2018YFC2000600)
Según 1 financiador declarado y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2024-02-02 · J Nutr Health Aging · vol. 28 · número 3 · pág. 100165
- Editorial
- Springer Science+Business Media
- Citado
- 24 citas · más que el 86% de estudios similares · 1.8× el promedio de su campo
- Referencias
- 77 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY-NC-ND
- Áreas de investigación
- Dietary Effects on Health · Diet and metabolism studies · Obesity, Physical Activity, Diet
- Palabras clave
- intermittent fasting, obesity, overweight, fat loss, body composition, fat mass, lean body mass, body weight, body mass index, triglycerides, middle-aged and older adults, weight loss diet, lipid profile, long-term weight maintenance, energy intake
- MeSH
- humans, obesity, weight loss, body mass index, diet, reducing, body composition, adult, aged, middle aged, female, male, overweight, randomized controlled trials as topic, intermittent fasting
10 autores
- Ke Yao🇨🇳Beijing Sport University
- Hao Su🇨🇳 · autor de correspondenciaBeijing Sport University
- Kaiyin Cui🇨🇳Beijing Sport University
- Ye Gao🇨🇳Beijing Sport University
- Dengyun Xu🇨🇳Beijing Sport University
- Qian Wang🇨🇳Beijing Sport University
- Zhitong Ha🇨🇳Beijing Sport University
- Teng Zhang🇨🇳Beijing Sport University
- Shuning Chen🇨🇳Beijing Sport University
- Tao Liu🇨🇳Beijing Sport University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objective
As the number of adults aged over 40 with obesity increases dramatically, intermittent fasting interventions (IF) may help them to lose fat and weight. This systematic review investigated the most recent research on the effects of intermittent fasting and a regular diet on body composition and lipids in adults aged over 40 with obesity without the metabolic disease.
Data sources
Randomized controlled trials (RCTs) on IF on adults aged over 40 with obesity were retrieved from PubMed, Web of Science, EBSCO, China Knowledge Network (CNKI), VIP database, Wanfang database with the experimental group using IF and the control group using a regular diet. Revman was used for meta-analysis. Effect sizes are expressed as weighted mean differences (WMD) and 95% confidence intervals (CI).
Study selection
A total of 9 articles of randomised controlled trials that met the requirements were screened for inclusion. Studies typically lasted 2-6 weeks. The experimental population was aged 42-66 years, with a BMI range of 25.7-35 kg/m2.
Synthesis
A total of 9 RCTs were included. meta-analysis showed that body weight (MD: -2.05 kg; 95% CI (-3.84, -0.27); p = 0.02), BMI (MD: -0.73 kg/m2; 95% CI (-1.05, -0.41); p < 0.001), fat mass (MD: -2.14 kg; 95% CI (-3.81, 0.47); p = 0.01), and TG (MD = -0.32 mmol/L, 95% CI (-0.50, -0.15, p < 0.001) were significantly lower in the experimental group than in the control group. No significant reduction in lean body mass (MD: -0.31 kg; 95% CI (-0.96, 0.34); p = 0.35).
Conclusion
IF had a reduction in body weight, BMI, fat mass, and TG in adults aged over 40 with obesity without metabolic disease compared to RD, and IF did not cause a significant decrease in lean body mass, which suggests healthy and effective fat loss. However, more long-term and high-quality trials are needed to reach definitive conclusions.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC-ND).
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