Does early time-restricted eating reduce body weight and preserve fat-free mass in adults? A systematic review and meta-analysis of randomized controlled trials
He M, Li B, Li M, Gao S
Diabetes & metabolic syndrome · 11 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Natural Science Foundation of China
- Gobierno
- Beijing Municipal Health Commission
- Universidad u hospital
- Chinese Academy of Medical Sciences
- Universidad u hospital
- Peking Union Medical College Hospital
- Universidad u hospital
- Chinese Academy of Medical Sciences & Peking Union Medical College
Según 5 financiadores declarados.
Publicación
- Publicado
- 2024-02-01 · Diabetes Metab Syndr · vol. 18 · número 2 · pág. 102952
- Editorial
- Elsevier BV
- Citado
- 15 citas · más que el 76% de estudios similares · 1.1× el promedio de su campo
- Referencias
- 74 trabajos
- Acceso
- De pago
- Áreas de investigación
- Dietary Effects on Health · Diet and metabolism studies · Nutritional Studies and Diet
- Palabras clave
- time-restricted eating, weight loss, fat mass, visceral fat, waist circumference, TNF-α, inflammation, metabolic health, fasting-mimicking diet, intermittent fasting, adults, sleep timing, circadian rhythm, satiety
- MeSH
- humans, body weight, weight loss, prognosis, fasting, time factors, adult, randomized controlled trials as topic
4 autores
- Mengyu He🇨🇳Chinese Academy of Medical Sciences & Peking Union Medical College; Peking Union Medical College Hospital
- Bo Li🇨🇳Chinese Academy of Medical Sciences & Peking Union Medical College; Peking Union Medical College Hospital
- Ming Li🇨🇳 · autor de correspondenciaChinese Academy of Medical Sciences & Peking Union Medical College; Peking Union Medical College Hospital
- Shan Gao🇨🇳 · autor de correspondenciaCapital Medical University; Xuan Wu Hospital of the Capital Medical University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
This meta-analysis evaluated whether weight loss caused by early time-restricted eating could promote fat mass loss while preserving fat-free mass, thereby leading to improvements in inflammation and metabolic health.
Methods
Relevant randomized controlled trials (RCTs) published up to March 28, 2023, were identified in six databases, including PubMed, Web of Science, and Embase.
Results
We initially screened 1279 articles, thirteen RCTs with 859 patients were ultimately included. Compared with nontime-restricted eating, early time-restricted eating significantly reduced body weight (-1.84 kg [-2.28, -1.41]; I2 = 56 %; P 2 = 42 %; P 2 = 43 %; P 2 [-13.76, -5.75]; I2 = 2 %; P 2 = 42 %; P 2 = 59 %; P = 0.06). Subgroup analysis showed that the early time-restricted eating of the 16:08 (fasting-time versus eating-time) strategy had a superior effect on preserving fat-free mass (-0.25 kg [-0.68, 0.18]; I2 = 0 %; P = 0.25) while significantly reducing body weight (-1.60 kg [-2.09, -1.11]; I2 = 0 %; P < 0.001) and improving metabolic outcomes.
Conclusions
Early time-restricted eating, especially 16:08 strategy, appears to be an effective strategy to decrease body weight, fat mass, abdominal obesity and inflammation, but less likely to decrease fat-free mass.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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