Financiado en parte por AstraZeneca
Risks and Benefits of Intermittent Fasting for the Aging Cardiovascular System
Ozcan M, Abdellatif M, Javaheri A, Sedej S
The Canadian journal of cardiology · 17 citas
Etiquetas de revisión
Financiado por la industriaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Revisión sistemática (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiado por la industria
- Organización sin fines de lucro
- Longer Life Foundation
- Empresa
- AstraZeneca
- Universidad u hospital
- Children's Discovery Institute
- Universidad u hospital
- St. Louis Children's Hospital
- Gobierno
- European Commission
- Gobierno
- Austrian Science Fund
- Universidad u hospital
- Medizinische Universität Graz
- Organización sin fines de lucro
- Österreichische Kardiologische Gesellschaft
- Universidad u hospital
- BioTechMed-Graz
- Gobierno
- National Institutes of Health
- Gobierno
- National Heart, Lung, and Blood Institute
- Organización sin fines de lucro
- Children's Discovery Institute
- Gobierno
- NIDDK NIH HHS
- Gobierno
- NHLBI
- Universidad u hospital
- St. Louis Children's Hospital
- Gobierno
- NIH
- Gobierno
- Austrian Science Fund FWF
- Gobierno
- NHLBI NIH HHS
- Organización sin fines de lucro
- Austrian Society of Cardiology
- Universidad u hospital
- BioTechMed-Graz Office
- Subvenciones
- Austrian Science Fund (P 34926); Children's Discovery Institute (MC-FR-2020-919); European Commission (H2020‐MSCA‐IF); National Institutes of Health (P30-DK020579); National Institutes of Health (P30DK056341)
Según 20 financiadores declarados.
Publicación
- Publicado
- 2024-02-12 · Can J Cardiol · vol. 40 · número 8 · págs. 1445–1457
- Editorial
- Elsevier BV
- Citado
- 19 citas · más que el 95% de estudios similares · 4.5× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 189 trabajos
- Acceso
- Acceso abierto (revista híbrida) · CC-BY
- Áreas de investigación
- Dietary Effects on Health · Nutritional Studies and Diet · Birth, Development, and Health
- Palabras clave
- intermittent fasting, cardiovascular aging, cardiovascular disease prevention, cardiometabolic health, blood pressure, glycemic control, weight loss, body composition, major adverse cardiovascular events, older adults, clinical trial design
- MeSH
- cardiovascular system, humans, cardiovascular diseases, risk assessment, risk factors, aging, intermittent fasting
4 autores
- Mualla Özcan🇺🇸Washington University in St. Louis
- Mahmoud Abdellatif🇦🇹Medical University of Graz; BioTechMed-Graz
- Ali Javaheri🇺🇸Washington University in St. Louis; John Cochran VA Medical Center
- Simon Sedej🇦🇹🇸🇮 · autor de correspondenciaMedical University of Graz; University of Maribor; BioTechMed-Graz
Resumen
El texto original del estudio, en el idioma en que se publicó.
Population aging and the associated increase in cardiovascular disease rates pose serious threats to global public health. Different forms of fasting have become an increasingly attractive strategy to directly address aging and potentially limit or delay the onset of cardiovascular diseases. A growing number of experimental studies and clinical trials indicate that the amount and timing of food intake as well as the daily time window during which food is consumed, are crucial determinants of cardiovascular health. Indeed, intermittent fasting counteracts the molecular hallmarks of cardiovascular aging and promotes different aspects of cardiometabolic health, including blood pressure and glycemic control, as well as body weight reduction. In this report, we summarize current evidence from randomized clinical trials of intermittent fasting on body weight and composition as well as cardiovascular and metabolic risk factors. Moreover, we critically discuss the preventive and therapeutic potential of intermittent fasting, but also possible detrimental effects in the context of cardiovascular aging and related disease. We delve into the physiological mechanisms through which intermittent fasting might improve cardiovascular health, and raise important factors to consider in the design of clinical trials on the efficacy of intermittent fasting to reduce major adverse cardiovascular events among aged individuals at high risk of cardiovascular disease. We conclude that despite growing evidence and interest among the lay and scientific communities in the cardiovascular health-improving effects of intermittent fasting, further research efforts and appropriate caution are warranted before broadly implementing intermittent fasting regimens, especially in elderly persons.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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