The Effect of Creatine Nitrate and Caffeine Individually or Combined on Exercise Performance and Cognitive Function: A Randomized, Crossover, Double-Blind, Placebo-Controlled Trial
Mabrey G, Koozehchian MS, Newton AT, Naderi A, Forbes SC, Haddad M
Nutrients · 14 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Jacksonville State University
Según 1 financiador declarado y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2024-03-07 · Nutrients · vol. 16 · número 6 · pág. 766
- Editorial
- Multidisciplinary Digital Publishing Institute
- Citado
- 19 citas · más que el 94% de estudios similares · 3.6× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 60 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Muscle metabolism and nutrition · Coffee research and impacts · Sports Performance and Training
- Palabras clave
- caffeine, combination supplementation, exercise performance, cognitive function, resistance-trained athletes, Stroop interference, anaerobic power, cardiovascular response, dietary supplements
- MeSH
- humans, nitrates, creatine, caffeine, exercise, cross-over studies, double-blind method, cognition, dietary supplements, male
6 autores
- Gina Mabrey🇺🇸Jacksonville State University
- M Koozehchian🇺🇸 · autor de correspondenciaJacksonville State University
- Andrew T. Newton🇺🇸Jacksonville State University
- Alireza Naderi🇮🇷Islamic Azad University Boroujerd Branch
- Scott C. Forbes🇨🇦Brandon University
- Monoem Haddad🇶🇦Qatar University
Resumen
El texto original del estudio, en el idioma en que se publicó.
This study examined the effect of creatine nitrate and caffeine alone and combined on exercise performance and cognitive function in resistance-trained athletes. In a double-blind, randomized crossover trial, twelve resistance-trained male athletes were supplemented with 7 days of creatine nitrate (5 g/day), caffeine (400 mg/day), and a combination of creatine nitrate and caffeine. The study involved twelve resistance-trained male athletes who initially provided a blood sample for comprehensive safety analysis, including tests for key enzymes and a lipid profile, and then performed standardized resistance exercises-bench and leg press at 70% 1RM-and a Wingate anaerobic power test. Cognitive function and cardiovascular responses were also examined forty-five minutes after supplementation. Creatine nitrate and caffeine that were co-ingested significantly enhanced cognitive function, as indicated by improved scores in the Stroop Word-Color Interference test (p = 0.04; effect size = 0.163). Co-ingestion was more effective than caffeine alone in enhancing cognitive performance. In contrast, no significant enhancements in exercise performance were observed. The co-ingestion of creatine nitrate and caffeine improved cognitive function, particularly in cognitive interference tasks, without altering short-term exercise performance. Furthermore, no adverse events were reported. Overall, the co-ingestion of creatine nitrate and caffeine appears to enhance cognition without any reported side effects for up to seven days.
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