Adherence to the ultra-processed dietary pattern and risk of depressive outcomes: Findings from the NutriNet Brasil cohort study and an updated systematic review and meta-analysis
Werneck AO, Steele EM, Delpino FM, Lane MM, Marx W, Jacka FN, Stubbs B, Touvier M, Srour B, Louzada ML, Levy RB, Monteiro CA
Clinical nutrition (Edinburgh, Scotland) · 20 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- Diarios o recordatorios de alimentación
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Fundação de Amparo à Pesquisa do Estado de São Paulo
- Gobierno
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Gobierno
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Gobierno
- Ministério da Saúde
- Subvenciones
- Fundação de Amparo à Pesquisa do Estado de São Paulo (2019/24,124–7); Conselho Nacional de Desenvolvimento Científico e Tecnológico (404211/2020-8); Fundação de Amparo à Pesquisa do Estado de São Paulo (22/05636-0)
Según 4 financiadores declarados.
Publicación
- Publicado
- 2024-04-01 · Clin Nutr · vol. 43 · número 5 · págs. 1190–1199
- Editorial
- Elsevier BV
- Citado
- 38 citas · más que el 96% de estudios similares · 4.7× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 64 trabajos
- Acceso
- Acceso abierto (copia en repositorio) · CC-BY
- Áreas de investigación
- Nutritional Studies and Diet · Consumer Attitudes and Food Labeling · Fatty Acid Research and Health
- Palabras clave
- ultra-processed foods, depressive symptoms, depression risk, diet and mental health, dietary adherence
- MeSH
- humans, diet, risk factors, cohort studies, prospective studies, depression, patient compliance, adult, middle aged, female, male, food, processed
12 autores
- André O. Werneck🇧🇷Universidade de São Paulo
- Eurídice Martínez Steele🇧🇷Universidade de São Paulo
- Felipe Mendes Delpino🇧🇷Universidade Federal de Pelotas
- Melissa M. Lane🇦🇺Barwon Health; Deakin University
- Wolfgang Marx🇦🇺Barwon Health; Deakin University
- Felice N. Jacka🇦🇺Barwon Health; Deakin University
- Brendon Stubbs🇬🇧King's College London
- Mathilde Touvier🇫🇷Inserm; Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement; Université Sorbonne Paris Nord; Equipe de Recherche en Epidémiologie Nutritionnelle; Centre de Recherche Épidémiologie et Statistique
- Bernard Srour🇫🇷Inserm; Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement; Université Sorbonne Paris Nord; Equipe de Recherche en Epidémiologie Nutritionnelle; Centre de Recherche Épidémiologie et Statistique
- Maria Laura da Costa Louzada🇧🇷Universidade de São Paulo
- Renata Bertazzi Levy🇧🇷Universidade de São Paulo
- Carlos Augusto Monteiro🇧🇷 · autor de correspondenciaUniversidade de São Paulo
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background & aims
We aimed to analyze the prospective association between adherence to the ultra-processed dietary pattern and risk of depressive outcomes using original data from the NutriNet Brasil cohort and via a systematic review and meta-analysis of observational studies that have investigated the same association.
Methods
In our original research analysis, we used data from 15,960 adults (≥18 y) participating in the NutriNet Brasil cohort study, free of depression or depressive symptoms during the baseline (77.5% women, 45.8 ± 13.0 y). The mean dietary share of ultra-processed foods (%Kcal/d), calculated from two baseline 24-h dietary recalls, was used to measure the adherence to the ultra-processed dietary pattern. New cases of depressive symptoms were assessed using the Patient Health Questionnaire-9 over the follow-up period (mean: 18.3 months). Cox proportional hazards models were used for the main analyses. In our systematic review and meta-analysis, we incorporated effect estimates from six prospective cohort studies that have examined the same association, including ours.
Results
In the adjusted model, each 10% increase in the dietary share of ultra-processed foods was associated with a 10% increase in the hazard of incident cases of depressive symptoms (HR:1.10; 95%CI: 1.07-1.14). This association was slightly attenuated in the models including potential mediators. In our meta-analysis of six prospective studies, high versus low exposure to ultra-processed foods was associated with a summary hazard ratio of depressive outcomes of 1.32; 95%CI: 1.19-1.46; I2: 71%.
Conclusion
A higher adherence to the ultra-processed dietary pattern was associated with a higher risk of developing depressive outcomes in the NutriNet Brasil cohort and in the meta-analysis.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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