Effects of dietary nitrate supplementation on oral health and associated markers of systemic health: a systematic review
Alhulaefi SS, Watson AW, Ramsay SE, Jakubovics NS, Matu J, Griffiths A, Kimble R, Siervo M, Brandt K, Shannon OM
Critical reviews in food science and nutrition · 11 citas
Cómo se estudió
- Diseño
- Revisión sistemática (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Taif University
- Universidad u hospital
- Taif University, Taif, KSA
Según 2 financiadores declarados.
Publicación
- Publicado
- 2024-05-11 · Crit Rev Food Sci Nutr · vol. 65 · número 14 · págs. 2813–2828
- Editorial
- Taylor & Francis
- Citado
- 13 citas · más que el 80% de estudios similares · 1.8× el promedio de su campo
- Referencias
- 58 trabajos
- Acceso
- Acceso abierto (revista híbrida) · CC-BY
- Áreas de investigación
- Oral microbiology and periodontitis research · Salivary Gland Disorders and Functions · Dental Erosion and Treatment
- Palabras clave
- Medicine, Nitrate, CINAHL, Cochrane Library, Oral Microbiome, Randomized controlled trial, Saliva, Meta-analysis, Systematic review, Physiology, Environmental health, Food science, MEDLINE, Internal medicine, Psychological intervention, Biology, Disease, Biochemistry
- MeSH
- saliva, humans, beta vulgaris, gingivitis, nitrates, diet, hydrogen-ion concentration, dietary supplements, oral health, randomized controlled trials as topic, microbiota, biomarkers, fruit and vegetable juices
10 autores
- Shatha S. Alhulaefi🇸🇦🇧🇪🇬🇧Taif University; Nutrition Sciences (Belgium); Newcastle University
- Anthony Watson🇧🇪🇬🇧Nutrition Sciences (Belgium); Newcastle University
- Sheena E Ramsay🇬🇧Newcastle University
- Nick S. Jakubovics🇬🇧Newcastle Dental Hospital; Newcastle University
- Jamie Matu🇬🇧Leeds Beckett University
- Alex Griffiths🇬🇧Leeds Beckett University
- Rachel Kimble🇷🇸🇬🇧Center for Health, Exercise and Sport Sciences; University of the West of Scotland
- Mario Siervo🇦🇺Curtin University
- Kirsten Brandt🇧🇪🇬🇧Nutrition Sciences (Belgium); Newcastle University
- Oliver Michael Shannon🇧🇪🇬🇧 · autor de correspondenciaNutrition Sciences (Belgium); Newcastle University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Poor oral health can impact an individual's ability to eat and has been associated with an increased risk of non-communicable diseases. While the benefits of nitrate consumption on oral health were first proposed more than 20 years ago, no systematic review has been published examining effects of dietary nitrate on oral health. This systematic review investigated the effects of dietary nitrate on markers of oral health in vivo in randomized controlled trials (RCTs). Five databases (PubMed, The Cochrane Library, CINAHL, MEDLINE, and SPORTDiscus) were searched from inception until March 2023. Nine articles reporting data on 284 participants were included. Dietary nitrate was provided via beetroot juice in most studies. The duration of the interventions ranged from one day to six weeks. Dietary nitrate supplementation increased the relative abundance of several individual bacterial genera including Neisseria and Rothia. Dietary nitrate supplementation increased salivary pH and decreased salivary acidification following consumption of a sugar-sweetened beverage. Furthermore, dietary nitrate supplementation resulted in a decrease in the gingival inflammation index. The results of this systematic review suggest that dietary nitrate could represent a potential nutritional strategy to positively modify oral health by impacting the oral microbiome, altering salivary pH, and minimizing gingival inflammation.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.