Exploring the link: magnesium intake and hepatic steatosis in Americans
Chen X, Fu L, Zhu Z, Wang Y
Frontiers in nutrition · 2 citas
Cómo se estudió
- Diseño
- Estudio transversal (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
Según la declaración de financiación del texto completo.
Publicación
- Publicado
- 2024-05-23 · Front Nutr · vol. 11 · pág. 1367174
- Editorial
- Frontiers Media
- Citado
- 2 citas · más que el 57% de estudios similares · 0.4× el promedio de su campo
- Referencias
- 27 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Magnesium in Health and Disease · Parathyroid Disorders and Treatments · Bone health and osteoporosis research
- Palabras clave
- Steatosis, Medicine, Magnesium, Confounding, National Health and Nutrition Examination Survey, Internal medicine, Fatty liver, Transient elastography, Population, Gastroenterology, Cirrhosis, Environmental health, Chemistry
4 autores
- Xingxing Chen🇨🇳Wenzhou Medical University
- Liying Fu🇨🇳Blood Center of Zhejiang Province
- Zhongxin Zhu🇨🇳Wenzhou Medical University
- Yunchao Wang🇨🇳 · autor de correspondenciaThe First People's Hospital of Xiaoshan District, Hangzhou
Resumen
El texto original del estudio, en el idioma en que se publicó.
Purpose
The connection between magnesium and hepatic steatosis has not been well-studied. This study aimed to explore the link between magnesium intake and hepatic steatosis, utilizing data from the National Health and Nutrition Examination Survey (NHANES) 2017-2020.
Materials and methods
The analysis included 5,935 participants, excluding individuals with hepatitis infection or substantial alcohol consumption. Magnesium intake assessment was based on 24-h dietary recalls. Hepatic steatosis evaluation employed the controlled attenuation parameter (CAP), measured via transient elastography. Multivariate regression and subgroup analyses were conducted to scrutinize the relationship between magnesium intake and CAP values.
Results
A higher magnesium intake was associated with lower CAP values, after adjusting for potential confounders. Subgroup analyses indicated an inverted U-shaped correlation between magnesium intake and CAP in women, White people, and non-hypertensive individuals, with respective inflection points at 126, 124.5, and 125 mg/day, respectively. Below these thresholds, a higher magnesium intake correlated with increased CAP values, while above these points, it was associated with decreased CAP.
Conclusion
This extensive population-based study indicates an inverse relationship between magnesium intake and hepatic steatosis in Americans. This relationship displays an inverted U-curve, varying before and after specified inflection points in women, White people, and non-hypertensive individuals. These findings offer insights into tailored magnesium supplementation strategies for preventing and treating liver steatosis, based on gender and ethnicity.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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