Isocaloric replacement of ultraprocessed foods was associated with greater weight loss in the POUNDS Lost trial
Yao Q, de Araujo CD, Juul F, Champagne CM, Bray GA, Sacks FM, Vadiveloo MK
Obesity (Silver Spring, Md.) · 7 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- Diarios o recordatorios de alimentación
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Heart, Lung, and Blood Institute
- Gobierno
- National Center for Research Resources
- Gobierno
- NHLBI NIH HHS
- Gobierno
- NCRR NIH HHS
- Subvenciones
- National Heart, Lung, and Blood Institute (K01HL165104); National Heart, Lung, and Blood Institute (U01 HL-073286); National Center for Research Resources (M01 RR002635)
Según 4 financiadores declarados.
Publicación
- Publicado
- 2024-06-27 · Obesity (Silver Spring) · vol. 32 · número 7 · págs. 1281–1289
- Editorial
- Wiley
- Citado
- 8 citas · más que el 92% de estudios similares · 3.1× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 39 trabajos
- Acceso
- Acceso abierto (copia en repositorio)
- Áreas de investigación
- Consumer Attitudes and Food Labeling · Nutrition, Genetics, and Disease · Nutritional Studies and Diet
- Palabras clave
- Medicine, Waist, Overweight, Weight loss, Animal science, Obesity, Trunk, Circumference, Demography, Internal medicine, Biology, Mathematics
- MeSH
- humans, obesity, weight loss, body mass index, diet, reducing, prospective studies, energy intake, food handling, adult, middle aged, female, male, overweight, waist circumference, fast foods
7 autores
- Qisi Yao🇺🇸University of Rhode Island
- Carolina Araujo🇺🇸University of Rhode Island
- Filippa Juul🇺🇸New York University
- Catherine M. Champagne🇺🇸Pennington Biomedical Research Center
- George A. Bray🇺🇸Pennington Biomedical Research Center
- Frank M. Sacks🇺🇸Brigham and Women's Hospital; Harvard University
- Maya K. Vadiveloo🇺🇸 · autor de correspondenciaUniversity of Rhode Island
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objective
Higher intake of ultraprocessed foods (UPFs) is associated with obesity. We examined whether replacing UPFs (NOVA 4) with minimally processed foods and culinary ingredients (NOVA 1 + 2) was associated with differential weight change in this secondary prospective analysis of the Preventing Overweight Using Novel Dietary Strategies (POUNDS) Lost trial.
Methods
We estimated percent energy intake (%kcal) from the four NOVA groups using 24-h dietary recalls in a subset of 356 participants. Multivariable-adjusted substitution models examined whether replacing %kcal from UPFs with NOVA 1 + 2 was associated with greater weight, body fat percentage, trunk fat, and waist circumference reduction at 6 months; changes in parameters were compared among NOVA 1 + 2 tertiles (T).
Results
Participants were on average 52.3 years of age, 85% White, 55% female, and 58.2% nonsmoking, with a mean BMI of 32.7 kg/m2. Replacing 10%kcal of UPFs with NOVA 1 + 2 was associated with greater 6-month weight (ß = 0.51, 95% CI: -0.93 to -0.09, p = 0.02), body fat percentage (ß = 2.7, 95% CI: -5.10 to -0.43, p = 0.02), and trunk fat reduction (ß = 3.9, 95% CI: -7.01 to -0.70, p = 0.02), but not waist circumference reduction. Participants in T3 (-8.33 kg) versus T1 (-5.32 kg) of NOVA 1 + 2 had greater weight loss (p < 0.001).
Conclusions
Isocaloric substitution of UPFs with NOVA 1 + 2 was associated with marginally greater weight loss under energy restriction. These modest findings support more research exploring the mechanisms linking UPFs with body weight regulation beyond energy intake.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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