Financiado en parte por AstraZeneca, Abbott Japan, Kowa Company, Astellas Pharma, Astellas Foundation for Research on Metabolic Disorders
Efficacy of long-term low carbohydrate diets for patients with type 2 diabetes: A systematic review and meta-analysis
Ichikawa T, Okada H, Hironaka J, Nakajima H, Okamura T, Majima S, Senmaru T, Ushigome E, Nakanishi N, Hamaguchi M, Joo E, Shide K, Fukui M
Journal of diabetes investigation · 10 citas
Etiquetas de revisión
Vínculos de autores con la industriaFinanciado por la industriaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiado por la industria
- Empresa
- AstraZeneca
- Empresa
- Abbott Japan
- Empresa
- Kowa Company
- Empresa
- Astellas Pharma
- Empresa
- Astellas Foundation for Research on Metabolic Disorders
- Organización sin fines de lucro
- Japan Diabetes Society
- Organización sin fines de lucro
- Mishima Kaiun Memorial Foundation
- Autores
- Al menos un autor declara un vínculo económico con la industria
Según 7 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2024-07-24 · J Diabetes Investig · vol. 15 · número 10 · págs. 1410–1421
- Editorial
- Asian Association for the Study of Diabetes
- Citado
- 17 citas · más que el 79% de estudios similares · 1.3× el promedio de su campo
- Referencias
- 49 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY-NC
- Áreas de investigación
- Diet and metabolism studies · Dietary Effects on Health · Diabetes Management and Research
- Palabras clave
- low-carbohydrate diet, type 2 diabetes, glycemic control, HbA1c, dyslipidemia, HDL cholesterol, triglycerides, weight loss, blood pressure, LDL cholesterol
- MeSH
- humans, diabetes mellitus, type 2, blood glucose, treatment outcome, blood pressure, diet, carbohydrate-restricted, randomized controlled trials as topic, glycemic control, glycated hemoglobin
13 autores
- Takahiro Ichikawa🇯🇵Kyoto Prefectural University of Medicine
- Hiroshi Okada🇯🇵 · autor de correspondenciaKyoto Prefectural University of Medicine
- Junya Hironaka🇯🇵Kyoto Prefectural University of Medicine
- Hanako Nakajima🇯🇵Kyoto Prefectural University of Medicine
- Takuro Okamura🇯🇵Kyoto Prefectural University of Medicine
- Saori Majima🇯🇵Kyoto Prefectural University of Medicine
- Takafumi Senmaru🇯🇵Kyoto Prefectural University of Medicine
- Emi Ushigome🇯🇵Kyoto Prefectural University of Medicine
- Naoko Nakanishi🇯🇵Kyoto Prefectural University of Medicine
- Masahide Hamaguchi🇯🇵Kyoto Prefectural University of Medicine
- Erina Joo🇯🇵Kyoto University Hospital
- Kenichiro Shide🇯🇵Kyoto University Hospital
- Michiaki Fukui🇯🇵Kyoto Prefectural University of Medicine
Resumen
El texto original del estudio, en el idioma en que se publicó.
Aims/introduction
Efficacy of long-term low-carbohydrate diets (LCD) to improve glycemic management for type 2 diabetes remains controversial. Thus, we investigated the association between long-term LCD and glycemic control in individuals with type 2 diabetes.
Materials and methods
We searched PubMed, Embase and the Cochrane Database for articles published up to June 2023, and included randomized controlled trials conducted on LCD interventions for >12 months in adults with type 2 diabetes. Primary outcome was the difference in glycated hemoglobin between long-term LCD and control groups. Additionally, we evaluated the differences in changes in systolic and diastolic blood pressure, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglyceride, and weight between long-term LCD and control groups.
Results
Six studies were identified and met the inclusion criteria. This study did not show significant differences in changes in glycated hemoglobin between long-term LCD and control diets (standardized mean difference -0.11, 95% confidence interval -0.33 to 0.11, P = 0.32). As with glycemic control, there were no significant differences in the changes in weight loss, blood pressure, and low-density lipoprotein cholesterol between long-term LCD and control diets. However, long-term LCD were associated with greater elevation in high-density lipoprotein cholesterol (standardized mean difference 0.22, 95% confidence interval 0.04-0.41; P = 0.02) and decrease in triglyceride (standardized mean difference -0.19; 95% confidence interval -0.37 to 0.02; P = 0.03) than that in control diets.
Conclusions
Our findings suggest efficacy of long-term LCD in treating dyslipidemia in individuals with type 2 diabetes, but do not recommend long-term LCD for glycemic control in the individuals.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC).
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.