Dietary magnesium intake and rheumatoid arthritis patients' all-cause mortality: evidence from the NHANES database
Liu H, Zhang K, Xiong L
Journal of health, population, and nutrition · 10 citas
Cómo se estudió
- Diseño
- Estudio de cohortes (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
Quién lo pagó
- Financiación
- Financiación independiente
Según la declaración de financiación del texto completo.
Publicación
- Publicado
- 2024-08-05 · J Health Popul Nutr · vol. 43 · número 1 · pág. 112
- Editorial
- BioMed Central
- Citado
- 10 citas · más que el 86% de estudios similares · 2.1× el promedio de su campo
- Referencias
- 47 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY-NC-ND
- Áreas de investigación
- Magnesium in Health and Disease · Parathyroid Disorders and Treatments · Rheumatoid Arthritis Research and Therapies
- Palabras clave
- Medicine, Hazard ratio, Rheumatoid arthritis, Internal medicine, Body mass index, Proportional hazards model, Confidence interval, Cause of death, Disease
- MeSH
- humans, arthritis, rheumatoid, magnesium, body mass index, diet, nutrition surveys, mortality, cause of death, proportional hazards models, databases, factual, adult, aged, middle aged, united states, female, male
3 autores
- Hantian Liu🇨🇳Nanchang University
- Kui Zhang🇨🇳West China Medical Center of Sichuan University
- Long Xiong🇨🇳 · autor de correspondenciaNanchang University; Second Affiliated Hospital of Nanchang University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Rheumatoid arthritis (RA) is a chronic inflammatory joint disease with all-cause mortality increasing globally. Dietary magnesium (Mg), an anti-inflammatory nutrient, has been proven to be associated with the all-cause mortality. The association of dietary Mg intake and all-cause mortality in RA patients remains unknown. The aim of this study was to assess the association between dietary Mg intake and all-cause mortality in RA patients.
Methods
RA patients were extracted from the NHANES 1999-2018, and followed for survival through December 31, 2019. Dietary Mg intake data were obtained from 24-h dietary recall interview. The association between dietary Mg intake and RA patients' all-cause mortality was explored based on weighted univariate and multivariate Cox proportional hazard models and described as absolute risk difference (ARD), hazard ratios (HRs) and 95% confidence intervals (CIs). This association was further explored in subgroup analyses based on different age, gender and body mass index (BMI).
Results
Totally 2,952 patients were included. Until 31 December 2019, a total of 825 deaths were documented. RA patients with higher dietary Mg intake had a 11.12% reduction of all-cause mortality (ARD=-11.12%; HR = 0.74, 95%CI: 0.56-0.99) in the fully adjusted model, especially in female (HR = 0.68, 95%CI: 0.47-0.98), aged 2 (HR = 0.62, 95%CI: 0.42-0.91).
Conclusion
RA patients who consumed adequate dietary Mg from diet as well as supplements may had a lower risk of all-cause mortality.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC-ND).
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