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Mediterranean diet enriched with olive oil shows no consistent benefits on cardiometabolic and anthropometric parameters: a systematic review with meta-analysis of randomized controlled trials

Keshani M, Sadeghi N, Tehrani SD, Ahmadi AR, Sharma M

European journal of nutrition · 9 citas

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Cómo se estudió

Diseño
Metaanálisis (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento
Consumo medido con
No se indica

Quién lo pagó

Financiación
Financiación no declarada

Publicación

Publicado
2024-08-17 · Eur J Nutr · vol. 63 · número 8 · págs. 2835–2857
Editorial
Springer Science+Business Media
Citado
10 citas · más que el 76% de estudios similares · 1.2× el promedio de su campo
Referencias
73 trabajos
Acceso
De pago
Áreas de investigación
Nutritional Studies and Diet · Edible Oils Quality and Analysis · Fatty Acid Research and Health
Palabras clave
Medicine, Mediterranean diet, Meta-analysis, Cochrane Library, Olive oil, Randomized controlled trial, CINAHL, MEDLINE, Environmental health, Internal medicine, Food science, Biology
MeSH
humans, cardiovascular diseases, lipids, triglycerides, anthropometry, diet, mediterranean, blood pressure, randomized controlled trials as topic, olive oil

5 autores

  • Mahdi Keshani🇮🇷 · autor de correspondenciaIsfahan University of Medical Sciences
  • Narges Sadeghi🇮🇷Ahvaz Jundishapur University of Medical Sciences
  • Sahar Dadkhah Tehrani🇮🇷Isfahan University of Medical Sciences
  • Amirhossein Ramezani Ahmadi🇮🇷Isfahan University of Medical Sciences
  • Manoj Sharma🇺🇸University of Nevada, Las Vegas

Resumen

El texto original del estudio, en el idioma en que se publicó.

Purpose

Cardiovascular disease (CVD) is the primary cause of death worldwide but there is a variation in its burden across some nations that seems to be related to dietary habits. Mediterranean populations have lower rates of morbidity and mortality from CVD. Thus, this systematic review and meta-analysis aimed to assess the impacts of the Mediterranean diet (MedDiet) enriched with olive oil on blood lipids, glycemic indices, blood pressure, and anthropometric indices.

Methods

A comprehensive search of the Web of Science, PubMed (MEDLINE), Scopus, Cochrane Library, Google Scholar, Embase, and CINAHL databases until March 2024 was conducted to identify clinical trials studying the effects of MedDiet enriched with olive oil on the aforementioned parameters.

Results

In total, 3303 records were retrieved. A total of 18 clinical trials met the inclusion criteria after records were screened for eligibility. According to the pooled analysis from the random-effects model, the MedDiet enriched with olive oil significantly reduced triglycerides (TG) compared with the control group (WMD = -2.40 mg/dl; 95%CI, -4.533 to -0.262; P = 0.027). Strong heterogeneity was observed. Sensitivity analysis did not change our results and no significant effect of any trial on the overall effect sizes of all variables were found. There was a concern about the reporting bias for some studies which reported some main outcomes.

Conclusion

MedDiet enriched with olive oil showed no consistent effects on any of the reported markers of cardiovascular health except on TG.

Systematic review registration

CRD42023424641.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.

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