Axial Length Shortening after Combined Repeated Low-Level Red-Light Therapy in Poor Responders of Orthokeratology in Myopic Children
Yu M, Tang X, Jiang J, Zhou F, Wang L, Xiang C, Hu Y, Yang X
Journal of ophthalmology · 9 citas
Cómo se estudió
- Diseño
- Ensayo clínico controlado (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Natural Science Foundation of China
- Gobierno
- Guangdong Science and Technology Department
- Gobierno
- Science and Technology Planning Project of Guangdong Province
- Gobierno
- Guangdong Provincial Department of Science and Technology
- Subvenciones
- Guangdong Science and Technology Department (2023A1111120013); National Natural Science Foundation of China (82371089); National Natural Science Foundation of China (30309010012226)
Según 4 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2024-01-01 · J Ophthalmol · vol. 2024 · número 1 · pág. 4133686
- Editorial
- Hindawi Publishing Corporation
- Citado
- 14 citas · más que el 94% de estudios similares · 3.4× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 27 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Ophthalmology and Visual Impairment Studies · Corneal surgery and disorders · Ocular Surface and Contact Lens
- Palabras clave
- Medicine, Orthokeratology, Red light, Optometry, Ophthalmology
8 autores
- Mengting Yu🇨🇳Sun Yat-sen University
- Xianghua Tang🇨🇳Sun Yat-sen University
- Jinyun Jiang🇨🇳Sun Yat-sen University
- Fengqi Zhou🇺🇸Mayo Clinic; Mayo Clinic Health System
- Lili Wang🇨🇳Sun Yat-sen University
- Chuqi Xiang🇨🇳Sun Yat-sen University
- Yin Chang Hu🇨🇳 · autor de correspondenciaSun Yat-sen University
- Xiao ke Yang🇨🇳 · autor de correspondenciaSun Yat-sen University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Purpose
To investigate the efficacy and safety of orthokeratology (ortho-k) and repeated low-level red-light (RLRL) therapy in treating poor responders of ortho-k in myopic children.
Methods
Study participants were 100 myopic children who completed two years of ortho-k treatment in a retrospective study. In the first year of ortho-k treatment (phase one), they experienced axial elongation of 0.30 mm or greater (defined as poor responders to ortho-k). Children were divided into two groups: the orthokeratology group (OK, n = 45) continued to receive ortho-k monotherapy and the combination group (OK-RLRL, n = 55) received RLRL in addition to ortho-k for the next year (phase two). Axial elongation over time between the groups was compared.
Results
The mean age, male-to-female ratio, axial length (AL), and axial elongation in phase one were comparable between OK and OK-RLRL groups (all P > 0.05). During phase two, significant AL shortening was observed in the OK-RLRL group compared with children in the OK group (-0.10 ± 0.16 mm vs 0.30 ± 0.19 mm, P β = -0.02), higher treatment compliance (β = -0.462), and AL change at 1 month (β = 1.263) were significantly associated with less AL elongation (all P < 0.05).
Conclusions
For poor responders of orthokeratology, RLRL could slow axial elongation in addition to the ortho-k treatment effect. Those who respond poorly to ortho-k with elder age might benefit more from combined therapy.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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