Ultra-processed foods, allergy outcomes and underlying mechanisms in children: An EAACI task force report
Berni Canani R, Carucci L, Coppola S, D'Auria E, O'Mahony L, Roth-Walter F, Vassilopolou E, Agostoni C, Agache I, Akdis C, De Giovanni Di Santa Severina F, Faketea G, Greenhawt M, Hoffman K, Hufnagel K, Meyer R, Milani GP, Nowak-Wegrzyn A, Nwaru B, Padua I, Paparo L, Diego P, Reese I, Roduit C, Smith PK, Santos A, Untersmayr E, Vlieg-Boerstra B, Venter C
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 38 citas
Cómo se estudió
- Diseño
- Revisión sistemática (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Organización sin fines de lucro
- European Academy of Allergy and Clinical Immunology
Según 1 financiador declarado.
Publicación
- Publicado
- 2024-09-01 · Pediatr Allergy Immunol · vol. 35 · número 9 · pág. e14231
- Editorial
- Wiley
- Citado
- 51 citas · más que el 100% de estudios similares · 19.5× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 104 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Consumer Attitudes and Food Labeling · Biochemical Analysis and Sensing Techniques · Nutrition, Genetics, and Disease
- Palabras clave
- Medicine, Allergy, Asthma, Food allergy, Hygiene hypothesis, Environmental health, Immunology, Pediatrics
- MeSH
- humans, asthma, food hypersensitivity, food handling, child, child, preschool, advisory committees, fast foods, rhinitis, allergic, gastrointestinal microbiome, food, processed
29 autores
- Roberto Berni Canani🇮🇹 · autor de correspondenciaCEINGE Biotecnologie Avanzate Franco Salvatore (Italy); University of Naples Federico II
- Laura R. Carucci🇮🇹CEINGE Biotecnologie Avanzate Franco Salvatore (Italy); University of Naples Federico II
- Serena Coppola🇮🇹CEINGE Biotecnologie Avanzate Franco Salvatore (Italy); University of Naples Federico II
- Enza D’Auria🇮🇹University of Milan
- Liam O’Mahony🇮🇪University College Cork; APC Microbiome Institute
- Franziska Roth‐Walter🇦🇹University of Vienna; University of Veterinary Medicine Vienna; Medical University of Vienna
- Emilia Vassilopolou🇬🇷🇮🇹International Hellenic University; University of Milan
- Carlo Virginio Agostoni🇮🇹University of Milan; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
- Ioana Octavia Agache🇷🇴Transylvania University of Brașov
- Cezmi A. Akdiş🇨🇭University of Zurich
- Fiorenza De Giovanni Di Santa Severina🇮🇹CEINGE Biotecnologie Avanzate Franco Salvatore (Italy); University of Naples Federico II
- Gavriela Faketea🇷🇴🇬🇷Iuliu Hațieganu University of Medicine and Pharmacy; General Hospital Pediatric Karamandanio
- Matt Greenhawt🇺🇸Children's Hospital Colorado; University of Colorado Denver
- Karin Hoffman🇦🇹Medical University of Vienna
- Karin Hufnagl🇦🇹University of Vienna; University of Veterinary Medicine Vienna; Medical University of Vienna
- Rosan W. Meyer🇬🇧🇧🇪University of Winchester; KU Leuven
- Gregorio Paolo Milani🇮🇹University of Milan; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
- Anna H Nowak-Wegrzyn🇵🇱University of Warmia and Mazury in Olsztyn
- Bright I. Nwaru🇸🇪University of Gothenburg
- Inês Pádua🇵🇹Cooperativa de Ensino Superior Politécnico e Universitário; CUF Porto Hospital
- Lorella Paparo🇮🇹CEINGE Biotecnologie Avanzate Franco Salvatore (Italy); University of Naples Federico II
- Diego Giampietro Peroni🇮🇹University of Pisa
- Imke Reese
- Caroline Roduit🇨🇭University of Bern; University Hospital of Bern; CK-CARE
- Peter Kenneth Smith🇦🇺Griffith University
- Alexandra F. Santos🇬🇧St Thomas' Hospital; King's College London; Evelina London Children's Healthcare
- Eva Untersmayr🇦🇹Medical University of Vienna
- B.J. Vlieg-Boerstra🇳🇱Rijnstate Hospital
- Carina Venter🇺🇸 · autor de correspondenciaChildren's Hospital Colorado; University of Colorado Denver
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Consumption of ultra-processed foods [UPFs] may be associated with negative health outcomes. Limited data exist regarding the potential role of UPFs in the occurrence of allergic diseases. The underlying mechanisms underpinning any such associations are also poorly elucidated.
Methods
We performed a systematic review and narrative evidence synthesis of the available literature to assess associations between UPF consumption and pediatric allergy outcomes (n = 26 papers), including data on the association seen with the gut microbiome (n = 16 papers) or immune system (n = 3 papers) structure and function following PRISMA guidelines.
Results
Dietary exposure to fructose, carbonated soft drinks, and sugar intake was associated with an increased risk of asthma, allergic rhinitis, and food allergies in children. Commercial baby food intake was associated with childhood food allergy. Childhood intake of fructose, fruit juices, sugar-sweetened beverages, high carbohydrate UPFs, monosodium glutamate, UPFs, and advanced glycated end-products (AGEs) was associated with the occurrence of allergic diseases. Exposure to UPFs and common ingredients in UPFs seem to be associated with increased occurrence of allergic diseases such as asthma, wheezing, food allergies, atopic dermatitis, and allergic rhinitis, in many, but not all studies.
Conclusion
More preclinical and clinical studies are required to better define the link between UPF consumption and the risk of allergies and asthma. These observational studies ideally require supporting data with clearly defined UPF consumption, validated dietary measures, and mechanistic assessments to definitively link UPFs with the risk of allergies and asthma.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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