Comparing the effects of time-restricted eating on glycaemic control in people with type 2 diabetes with standard dietetic practice: A randomised controlled trial
Parr EB, Radford BE, Hall RC, Steventon-Lorenzen N, Flint SA, Siviour Z, Plessas C, Halson SL, Brennan L, Kouw IWK, Johnston RD, Devlin BL, Hawley JA
Diabetes research and clinical practice · 24 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Organización sin fines de lucro
- Diabetes Australia
- Universidad u hospital
- Australian Catholic University
- Subvenciones
- Diabetes Australia (20YG-PARE)
Según 2 financiadores declarados.
Publicación
- Publicado
- 2024-10-15 · Diabetes Res Clin Pract · vol. 217 · pág. 111893
- Editorial
- Elsevier BV
- Citado
- 36 citas · más que el 98% de estudios similares · 8.1× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 44 trabajos
- Acceso
- Acceso abierto (revista híbrida) · CC-BY-NC
- Áreas de investigación
- Dietary Effects on Health · Enhanced Recovery After Surgery · Nutritional Studies and Diet
- Palabras clave
- Medicine, Type 2 diabetes, Diabetes mellitus, Control (management), Gerontology, Physical therapy, Endocrinology, Artificial intelligence
- MeSH
- humans, diabetes mellitus, type 2, obesity, blood glucose, dietetics, adult, aged, middle aged, female, male, glycemic control, glycated hemoglobin, intermittent fasting
13 autores
- Evelyn B. Parr🇦🇺 · autor de correspondenciaAustralian Catholic University
- Bridget E. Radford🇦🇺Australian Catholic University
- Rebecca C. Hall🇦🇺Australian Catholic University
- Nikolai Steventon-Lorenzen🇦🇺Australian Catholic University
- Steve A. Flint🇦🇺Australian Catholic University
- Zoe Siviour🇦🇺Australian Catholic University
- Ch. T. Plessas🇦🇺Australian Catholic University
- Shona Leigh Halson🇦🇺Australian Catholic University
- Leah Brennan🇦🇺La Trobe University
- Imre W. K. Kouw🇳🇱Wageningen University & Research
- Rich D. Johnston🇦🇺Australian Catholic University
- Brooke L. Devlin🇦🇺The University of Queensland
- John A. Hawley🇬🇧🇦🇺Manchester Metropolitan University; Australian Catholic University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Aims
To test the efficacy of time-restricted eating (TRE) in comparison to dietitian-led individualised dietary guidance to improve HbA1c in people with Type 2 diabetes mellitus.
Methods
In a parallel groups design, 51 adults (35-65 y) with Type 2 diabetes mellitus and overweight/obesity (HbA1c ≥6.5% (48 mmol/mol), BMI ≥25-≤40 kg/m2) commenced a six-month intervention. Following baseline, participants were randomised to TRE (1000-1900 h) or DIET (individualised dietetic guidance) with four consultations over four months. Changes in HbA1c (primary), body composition, and self-reported adherence (secondary) were analysed using linear mixed models. A non-inferiority margin of 0.3% (4 mmol/mol) HbA1c was set a priori.
Results
Forty-three participants (56 ± 8 y, BMI: 33 ± 5 kg/m2, HbA1c: 7.6 ± 0.8%) completed the intervention. HbA1c was reduced (P=0.002; TRE: -0.4% (-5 mmol/mol), DIET: -0.3% (-4 mmol/mol)) with no group or interaction effects; TRE was non-inferior to DIET (-0.11%, 95%CI: -0.50% to 0.28%). Body mass reduced in both groups (TRE: -1.7 kg; DIET: -1.2 kg) via ∼900 kJ/d spontaneous energy reduction (P<0.001). Self-reported adherence was higher in TRE versus DIET (P<0.001).
Conclusions
When individualised dietary guidance is not available, effective, and/or suitable, TRE may be an alternative dietary strategy to improve glycaemic control in people with Type 2 diabetes mellitus.
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