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Metaanálisis2025Financiación no declaradaSolo mecanismos

Effect of the Mediterranean Diet Supplemented With Olive Oil Versus the Low-Fat Diet on Serum Inflammatory and Endothelial Indexes Among Adults: A Systematic Review and Meta-analysis of Clinical Controlled Trials

Pourrajab B, Fotros D, Asghari P, Shidfar F

Nutrition reviews · 8 citas

Etiquetas de revisión

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Cómo se estudió

Diseño
Metaanálisis (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Solo mecanismos
Consumo medido con
No se indica

Quién lo pagó

Financiación
Financiación no declarada

Publicación

Publicado
2024-10-10 · Nutr Rev · vol. 83 · número 7 · págs. e1421–e1440
Editorial
Oxford University Press
Citado
15 citas · más que el 86% de estudios similares · 1.9× el promedio de su campo
Referencias
88 trabajos
Acceso
De pago
Áreas de investigación
Nutritional Studies and Diet · Edible Oils Quality and Analysis · Fatty Acid Research and Health
Palabras clave
Mediterranean diet, Meta-analysis, Medicine, Olive oil, Context (archaeology), Internal medicine, MEDLINE, Clinical trial, Randomized controlled trial, Systematic review, Endothelial dysfunction, Inflammation, Gerontology, Physiology, Food science, Biology
MeSH
endothelium, vascular, humans, inflammation, diet, fat-restricted, diet, mediterranean, dietary supplements, adult, middle aged, female, male, controlled clinical trials as topic, olive oil

4 autores

  • Behnaz Pourrajab🇮🇷National Nutrition and Food Technology Research Institute; Shahid Beheshti University of Medical Sciences
  • Danial Fotros🇮🇷National Nutrition and Food Technology Research Institute; Shahid Beheshti University of Medical Sciences
  • Parastoo Asghari🇮🇷Mashhad University of Medical Sciences
  • Farzad Shidfar🇮🇷 · autor de correspondenciaIran University of Medical Sciences

Resumen

El texto original del estudio, en el idioma en que se publicó.

Context

Inflammation and endothelial dysfunction are important risk factors for chronic diseases, including cardiovascular diseases and related mortality.

Objective

This systematic review and meta-analysis aimed to assess the effects of 2 popular dietary patterns-a Mediterranean (MED) diet supplemented with olive oil and a low-fat diet (LFD)-on factors related to inflammation and endothelial function in adults.

Data sources and data extraction

The following online databases were searched for related studies published until August 7, 2024: PubMed/Medline, Scopus, Clarivate Analytics Web of Science, Cochrane Central Register of Controlled Trials, and Google Scholar. Two independent researchers selected the studies based on the eligibility criteria.

Data analysis

The effect sizes were expressed as Hedges' g with 95% CIs. A total of 16 eligible trials with 20 effect sizes were included in the analyses. This meta-analysis revealed that the MED diet supplemented with olive oil significantly improved all of the indicators of the study compared with the LFD, except in the case of E-selectin, in which a low and nonsignificant decrease was reported.

Conclusion

Available evidence suggests that a MED diet supplemented with olive oil compared with the LFD significantly improves inflammation and serum endothelial function in adults.

Systematic review registration

PROSPERO registration no. CRD42023485718.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.

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