Neuroanatomical and functional substrates of the short video addiction and its association with brain transcriptomic and cellular architecture
Gao Y, Hu Y, Wang J, Liu C, Im H, Jin W, Zhu W, Ge W, Zhao G, Yao Q, Wang P, Zhang M, Niu X, He Q, Wang Q
NeuroImage · 25 citas
Cómo se estudió
- Diseño
- Estudio transversal (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Natural Science Foundation of China
- Gobierno
- Ministry of Education of the People's Republic of China
- Gobierno
- Natural Science Foundation of Tianjin City
- Universidad u hospital
- Guilin Medical University
- Gobierno
- Natural Science Foundation of Tianjin-Science and Technology Correspondent Project
- Gobierno
- Natural Science Foundation of Tianjin Science and Technology Correspondent Project
- Gobierno
- Ministry of Education of the People's Republic of China
- Gobierno
- Natural Science Foundation of Tianjin Municipality
- Subvenciones
- National Natural Science Foundation of China (31972906); National Natural Science Foundation of China (32000786); Guilin Medical University (GKLBCN-202401-03); Natural Science Foundation of Tianjin-Science and Technology Correspondent Project (23JCYBJC00910)
Según 8 financiadores declarados.
Publicación
- Publicado
- 2025-01-16 · Neuroimage · vol. 307 · pág. 121029
- Editorial
- Elsevier BV
- Citado
- 40 citas · más que el 99% de estudios similares · 10.5× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 134 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY-NC
- Áreas de investigación
- Tryptophan and brain disorders · Functional Brain Connectivity Studies · Mental Health Research Topics
- Palabras clave
- short video addiction, social media addiction, dispositional envy, orbitofrontal cortex, cerebellum, dorsolateral prefrontal cortex, posterior cingulate cortex, temporal pole, spontaneous neuronal activity, gray matter volume, gene expression, excitatory and inhibitory neurons, representational similarity analysis, brain transcriptomics
- MeSH
- brain, cerebellum, prefrontal cortex, humans, magnetic resonance imaging, adolescent, adult, female, male, young adult, transcriptome, gray matter, internet addiction disorder
15 autores
- Yuanyuan Gao🇨🇳Tianjin Normal University
- Ying Hu🇨🇳Tianjin Normal University
- Jinlian Wang🇨🇳Tianjin Normal University
- Chang Liu🇨🇳Tianjin Normal University
- Hohjin Im
- Weipeng Jin🇨🇳Tianjin Huanhu Hospital
- Wenwei Zhu🇨🇳South China Normal University
- Wei Ge🇨🇳Tianjin Normal University
- Guang Wei Zhao🇨🇳Tianjin Normal University
- Qiong Yao🇨🇳Hefei Normal University
- Pinchun Wang🇨🇳Tianjin Normal University
- Manman Zhang🇨🇳Tianjin Normal University
- Xin Niu🇺🇸University of California, Los Angeles
- Qinghua He🇨🇳Southwest University
- Qiang Wang🇨🇳Tianjin Normal University; Beijing Normal University; State Key Laboratory of Cognitive Neuroscience and Learning
Resumen
El texto original del estudio, en el idioma en que se publicó.
Short video addiction (SVA) has emerged as a growing behavioral and social issue, driven by the widespread use of digital platforms that provide highly engaging, personalized, and brief video content. We investigated the neuroanatomical and functional substrates of SVA symptoms, alongside brain transcriptomic and cellular characteristics, using Inter-Subject Representational Similarity Analysis (IS-RSA) and transcriptomic approaches. Behaviorally, we found that dispositional envy was associated with SVA. Structurally, SVA was positively correlated with increased morphological volumes in the orbitofrontal cortex (OFC) and bilateral cerebellum. Functionally, the dorsolateral prefrontal cortex (DLPFC), posterior cingulate cortex (PCC), cerebellum, and temporal pole (TP) exhibited heightened spontaneous activity, which was positively correlated with SVA severity. Transcriptomic and cellular analyses also showed specific genes linked to gray matter volume (GMV) associated with SVA, with predominant expression in excitatory and inhibitory neurons. These genes showed distinct spatiotemporal expression patterns in the cerebellum during adolescence. This study offers a comprehensive framework integrating structural, functional, and neurochemical evidence to highlight the neural-transcriptomic underpinnings of SVA symptoms in a non-clinical population.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC).
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