Impact of repeated low-level red-light therapy on axial length, refraction, and macular retinal blood flow density in adolescents with mild to moderate myopia
Ji M, Ba T, Li H, Wang D, Zhang G, Wang W
Photodiagnosis and photodynamic therapy · 3 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Estudio de cohortes (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2025-01-30 · Photodiagnosis Photodyn Ther · vol. 52 · pág. 104499
- Editorial
- Elsevier BV
- Citado
- 5 citas · más que el 91% de estudios similares · 3.1× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 27 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY-NC-ND
- Áreas de investigación
- Ophthalmology and Visual Impairment Studies · Corneal surgery and disorders · Retinopathy of Prematurity Studies
- Palabras clave
- Retinal, Ophthalmology, Refraction, Medicine, Blood flow, Optometry, Optics, Physics, Internal medicine
- MeSH
- retinal vessels, macula lutea, humans, myopia, refraction, ocular, photochemotherapy, retrospective studies, adolescent, child, female, male, axial length, eye
6 autores
- Meiqi Ji
- Teer Ba🇨🇳Inner Mongolia Medical University
- Huixia Li
- Dongxue Wang
- Guisen Zhang · autor de correspondencia
- Wei Wang🇨🇳 · autor de correspondenciaWeifang People's Hospital; Weifang Chinese Medicine Hospital
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
In order to evaluate the effectiveness of repeated low-level red-light (RLRL) therapy on stabilizing axial elongation and refractive changes in adolescents with mild to moderate myopia. In addition, we also examined whether RLRL therapy affects retinal blood flow density in the macular region, a factor previously unstudied in this context.
Methods
Conducted at a single clinical site, this retrospective, single-arm study followed participants over six months, with assessments at baseline, 1 month, 3 months, and 6 months. The primary outcomes included axial length and spherical equivalent refraction (SER) changes. Secondary assessments included retinal blood flow density (superficial and deep macular layers), white-to-white corneal diameter, central corneal thickness, intraocular pressure (IOP), corneal curvature, light sensitivity, and peripheral retinal thickness.
Results
There were 32 enrolled participants (mean age = 11.5 ± 1.72) in the current study. The spherical equivalent (SER) remained relatively stable over the first three months, but it significantly improved at six months, changing from -2.39 ± 2.21 D at baseline to -2.01 ± 2.12 D (P 0.05), with no significant changes over the six months. There were no obvious side effects following the treatment.
Conclusions
Low-energy red light therapy shows promise as a non-invasive approach for stabilizing myopia in adolescents, with no observed compromise to retinal blood flow density. Further longitudinal research is needed to validate these findings and support clinical recommendations for myopia management.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC-ND).
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