Effect of egg consumption on health outcomes: An updated umbrella review of systematic reviews and meta-analysis of observational and intervention studies
Formisano E, Lopes Neri LC, Caffa I, Borgarelli C, Ferrando MR, Proietti E, Turrini F, Martini D, Angelino D, Tagliabue A, Pisciotta L
Nutrition, metabolism, and cardiovascular diseases : NMCD · 2 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2025-01-04 · Nutr Metab Cardiovasc Dis · vol. 35 · número 5 · pág. 103849
- Editorial
- Elsevier BV
- Citado
- 10 citas · más que el 90% de estudios similares · 2.9× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 71 trabajos
- Acceso
- Acceso abierto (revista híbrida) · OTHER-OA
- Áreas de investigación
- Nutritional Studies and Diet · Obesity, Physical Activity, Diet · Consumer Attitudes and Food Labeling
- Palabras clave
- Dyslipidemia, Medicine, Observational study, Meta-analysis, Systematic review, Internal medicine, Environmental health, MEDLINE, Obesity, Biology
- MeSH
- humans, neoplasms, risk assessment, risk factors, risk reduction behavior, health status, nutritive value, eggs, adult, middle aged, female, male, recommended dietary allowances, protective factors, biomarkers, observational studies as topic, diet, healthy
11 autores
- Elena Formisano🇮🇹Ospedale Policlinico San Martino; University of Genoa
- Lenycia de Cassya Lopes Neri🇮🇹University of Pavia
- Irene Caffa🇮🇹Ospedale Policlinico San Martino; University of Genoa
- Consuelo Borgarelli🇮🇹University of Genoa
- Maria Regina Ferrando🇮🇹University of Genoa
- Elisa Proietti🇮🇹University of Genoa
- Federica Turrini🇮🇹University of Genoa
- Daniela Martini🇮🇹University of Milan
- Donato Angelino🇮🇹University of Teramo
- Anna Tagliabue🇮🇹University of Pavia
- Livia Pisciotta🇮🇹 · autor de correspondenciaOspedale Policlinico San Martino; University of Genoa
Resumen
El texto original del estudio, en el idioma en que se publicó.
Aims
To evaluate the effect of egg consumption on health outcomes.
Data synthesis
A systematic search in PubMed, Scopus, Lilacs, and Web of Science was developed using terms ("egg consumption" or "egg intake") and ("health" or "chronic diseases" or "diabetes" or "cancer" or "cholesterol" or "dyslipidemia"), and meta-analyses of observational or interventional studies published since January 2020 were included. The studies' quality was evaluated through AMSTAR-2 and NutriGrade, and the strength of evidence according to sample size, heterogeneity, and quality of articles. Fourteen meta-analyses were included (10 observational, 4 interventional studies). The wide range of outcomes, with substantial variability and high heterogeneity, indicated a lack of robust evidence. The overall quality of studies was critically low. The level of evidence was very weak for all the significant associations: risk of heart failure (RR 1.15; 95%CI: 1.02-1.30), cancer mortality (RR 1.13; 95%CI 1.06-1.20), higher levels of LDL cholesterol (WMD 7.39; 95%CI 5.82-8.95), total cholesterol (WMD 9.12; 95%CI 7.35-10.89), and apolipoprotein B-100 (WMD 0.06; 95%CI 0.03-0.08). Conversely, egg intake has been weakly associated with improvements in HDL cholesterol (WMD 1.37; 95%CI 0.49-2.25), apolipoprotein A1 (WMD 0.03; 95%CI 0.01-0.05), and growth parameters in children (WMD 0.47; 95%CI 0.13-0.80). No evidence of association was found among all cardiovascular outcomes and all-cause mortality risk between high vs. low egg consumption.
Conclusion
Due to the critically low strength of studies, insufficient evidence is available to discourage egg consumption, suggesting eggs can be part of a healthy diet.
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