Impact of dietary magnesium intake on depression risk in American adults: a cross-sectional study of the National Health and Nutrition Examination Survey 2005-2020
Huang Y, Ruan S, Yang Y, Liang H, Chen S, Chang Q
Frontiers in nutrition · 1 cita
Cómo se estudió
- Diseño
- Estudio transversal (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- General Hospital of People’s Liberation Army
Según 1 financiador declarado y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2025-02-06 · Front Nutr · vol. 12 · pág. 1484344
- Editorial
- Frontiers Media
- Citado
- 2 citas · más que el 71% de estudios similares · 1.0× el promedio de su campo
- Referencias
- 41 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Magnesium in Health and Disease · Parathyroid Disorders and Treatments · Therapeutic Uses of Natural Elements
- Palabras clave
- National Health and Nutrition Examination Survey, Cross-sectional study, Environmental health, Medicine, Depression (economics), Gerontology, Population
6 autores
- Yanping Huang🇨🇳 · autor de correspondenciaFujian University of Traditional Chinese Medicine
- Su Ruan🇨🇳Fujian University of Traditional Chinese Medicine
- Yang Yang🇨🇳Fujian University of Traditional Chinese Medicine
- Hui Wen Liang🇨🇳Fujian University of Traditional Chinese Medicine
- Su Chen🇨🇳Fujian University of Traditional Chinese Medicine
- Qing Chang🇨🇳Fujian University of Traditional Chinese Medicine
Resumen
El texto original del estudio, en el idioma en que se publicó.
Introduction
Depression is a major global mental health challenge. Previous research suggests a link between magnesium consumption and depression, but the dose-response relationship remains unclear. This study investigates the relationship between dietary magnesium intake and depression risk among American adults.
Methods
Data from the 2005-2020 National Health and Nutrition Examination Survey (NHANES) were examined. Depression was measured with the Patient Health Questionnaire-9 (PHQ-9), and dietary magnesium consumption was calculated from two 24-h meal recalls. We used restricted cubic spline models, logistic regression, and sensitivity analyses to assess the connection.
Results
Among 35,252 participants (mean age: 49.5 ± 17.6 years; 49.9% women), we observed a nonlinearity in the relationship between dietary magnesium intake and depression. Below the inflection point (366.7 mg/day), the odds ratio (OR) was 0.998 (95% CI: 0.997-0.999, p p = 0.007). In participants aged ≥60 years, the association was inverse L-shaped, with magnesium intake ≥270.7 mg/day increasing depression incidence by 0.1% per 1 mg/d increase.
Conclusion
A nonlinear dose-response relationship exists between dietary magnesium intake and depression risk among US adults. Age significantly moderates this association, suggesting dietary recommendations should be tailored to different age groups.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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