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Supplementation of Creatine Monohydrate Improves Sprint Performance but Has no Effect on Glycolytic Contribution: A Nonrandomized, Placebo-Controlled Crossover Trial in Trained Cyclists

Meixner B, Stegmaier J, Renner P, Koehler K, Yang WH, Sperlich B

Current developments in nutrition · 8 citas

Cómo se estudió

Diseño
Ensayo clínico controlado (clasificado por nuestro filtro de IA)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento

Quién lo pagó

Financiación
Financiación independiente

Según la declaración de financiación del texto completo.

Publicación

Publicado
2025-01-28 · Curr Dev Nutr · vol. 9 · número 2 · pág. 104561
Editorial
Elsevier BV
Citado
9 citas · más que el 95% de estudios similares · 4.4× el promedio de su campo
Impacto
Entre el 10 % más citado de su campo
Referencias
66 trabajos
Acceso
Acceso abierto (revista) · CC-BY
Áreas de investigación
Muscle metabolism and nutrition · Exercise and Physiological Responses · Sports Performance and Training
Palabras clave
Sprint, Crossover study, Placebo, Randomized controlled trial, Physical therapy, Creatine, Medicine, Crossover, Physical medicine and rehabilitation, Psychology, Internal medicine, Computer science, Alternative medicine, Artificial intelligence

6 autores

  • Benedikt Johannes Meixner🇩🇪 · autor de correspondenciaFriedrich-Alexander-Universität Erlangen-Nürnberg; University of Würzburg
  • Johanna Stegmaier🇩🇪Friedrich-Alexander-Universität Erlangen-Nürnberg
  • Peter Renner
  • Karsten Koehler🇩🇪Technical University of Munich
  • Woo‐Hwi Yang🇰🇷CHA University
  • Billy Sperlich🇩🇪University of Würzburg

Resumen

El texto original del estudio, en el idioma en que se publicó.

Background

Sprint performance may be crucial for athletes in sprint and endurance sports. In this regard, the maximal glycolytic rate (νLamax) is a variable within Mader's model of metabolism that is commonly tested in a 15-s all-out sprint test. The product of lactate accumulation (ΔLa) and lactate distribution space approximated by fat-free mass (FFM) is strongly linked to sprint performance. Creatine monohydrate is a widely used ergogenic aid known for increasing anaerobic performance and FFM and the phosphagenic system contributes most to a 15-s all-out sprint.

Objectives

The aim of the study was to analyze the influence of creatine supplementation of 15-s work, FFM, and ΔLa.

Methods

Twenty male and 5 female cyclists underwent a placebo-controlled, crossover design with 4 laboratory visits. After a familiarization trial, baseline measurements were performed. Placebo (4 × 5 g/d maltodextrin) and creatine monohydrate (4 × 5 g/d) were administered for 5 d before the respective trials. All participants underwent this order of trials and performed a 15-s all-out sprint test on a Cyclus2-ergometer. Capillary blood was sampled before and every minute (for 8 min) after the sprint to determine ΔLa. Body composition was determined employing bioelectric impedance analysis.

Results

Creatine supplementation significantly increased 15-s work output and FFM compared with baseline and placebo conditions. However, no significant differences were found in capillary blood lactate accumulation (ΔLa) or glycolytic contribution.

Conclusions

The results indicate potential differences in limitations of sprint performance of participants. Responders to creatine supplementation are potentially limited by mechanical or metabolic factors. The findings of this study highlight the importance of considering supplementation of creatine monohydrate when undergoing testing for the maximal glycolytic rate.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).

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