Whole-body cryotherapy can reduce the inflammatory response in humans: a meta-analysis based on 11 randomized controlled trials
He J, Zhang X, Ge Z, Shi J, Guo S, Chen J
Scientific reports · 6 citas
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Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Solo mecanismos
Quién lo pagó
- Financiación
- Financiación independiente
Según la declaración de financiación del texto completo.
Publicación
- Publicado
- 2025-03-05 · Sci Rep · vol. 15 · número 1 · pág. 7759
- Editorial
- Nature Portfolio
- Citado
- 11 citas · más que el 90% de estudios similares · 2.7× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 58 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY-NC-ND
- Áreas de investigación
- Exercise and Physiological Responses · Tendon Structure and Treatment · Infrared Thermography in Medicine
- Palabras clave
- Randomized controlled trial, Meta-analysis, Cryotherapy, Medicine, MEDLINE, Inflammatory response, Bioinformatics, Internal medicine, Inflammation, Surgery, Biology
- MeSH
- humans, inflammation, interleukin-10, cryotherapy, interleukin-1beta, randomized controlled trials as topic
6 autores
- Jun He🇨🇳 · autor de correspondenciaNorthwestern Polytechnical University; China South Industries Group (China)
- Xinyu Zhang🇨🇳Jilin University
- Zhili Ge🇨🇳Jilin University
- Jingjing Shi🇨🇳Jilin University
- Shuwen Guo🇨🇳China South Industries Group (China)
- Jun Chen🇨🇳 · autor de correspondenciaNorthwestern Polytechnical University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Whole-body cryotherapy (WBC) is increasingly being studied and used in various populations, mainly focusing on improving the body's regenerative capacity. More comprehensive summaries of anti-inflammatory responses are needed. To systemically assess the effect of WBC on the inflammatory response in humans based on randomized controlled trials (RCTs). Articles about RCTs accessing the effects of whole-body cryotherapy on the levels of inflammatory factors in humans published until August 1, 2024 had been searched in PubMed, Web of Science, Embase and Cochrane library databases. The general information of the included articles and exposure mode, the types and levels of inflammatory factors in serum were extracted. The PEDro scale was used to assess the risk of bias, and the GRADE scale was used to assess the level of certainty of evidence. RevMan 5.4 software were used to conduct the meta-analysis. A total of 11 RCTs in 11 articles were included, and the total sample size was 274. The level of IL-1β in serum of people exposed to WBC was lower than that in control group (SMD value was - 2.08pg/mL, P < 0.05), and athletes exposed to WBC were more likely to benefit from this. The level of IL-10 in serum of people exposed to WBC was higher than that in control group ( SMD value was 0.78 pg/mL, P < 0.05), and obese people exposed to WBC were more likely to benefit from this than athletes. WBC effectively reduces inflammation by lowering IL-1β and increasing IL-10 levels, offering significant benefits for athletes and obese individuals.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC-ND).
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