Cardiometabolic and obesity risk outcomes of dawn-to-dusk, dry intermittent fasting: Insights from an umbrella review
Faris M, Abdelrahim DN, El Herrag SE, Khaled MB, Shihab KA, AlKurd R, Madkour M
Clinical nutrition ESPEN · 15 citas
Etiquetas de revisión
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Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2025-03-11 · Clin Nutr ESPEN · vol. 67 · págs. 127–145
- Editorial
- Elsevier BV
- Citado
- 14 citas · más que el 98% de estudios similares · 7.5× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 84 trabajos
- Acceso
- De pago
- Áreas de investigación
- Dietary Effects on Health · Diabetes, Cardiovascular Risks, and Lipoproteins · Birth, Development, and Health
- Palabras clave
- Ramadan fasting, cardiometabolic risk, obesity, glucose homeostasis, insulin resistance, blood pressure, lipid profile, body composition, fasting blood glucose, leptin, adiponectin, weight loss, waist circumference, HOMA-IR, HbA1c, triglycerides, HDL cholesterol, LDL cholesterol
- MeSH
- humans, cardiovascular diseases, insulin resistance, obesity, insulin, blood glucose, body mass index, fasting, risk factors, blood pressure, islam, female, male, waist circumference, cardiometabolic risk factors, intermittent fasting
7 autores
- MoezAlIslam E. Faris🇯🇴Applied Science Private University
- Dana N. Abdelrahim🇦🇪University of Sharjah
- Salah Eddine El Herrag🇩🇿Université Djilali de Sidi Bel Abbès
- Méghit Boumediène Khaled🇩🇿Université Djilali de Sidi Bel Abbès
- Katia Abu Shihab🇦🇪University of Sharjah
- Refat Ahmad Fawzi Alkurd🇯🇴Petra University
- Mohammed Madkour🇦🇪University of Sharjah
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background & aims
This umbrella review comprehensively and systematically summarizes meta-analyses on the impact of dawn-to-dusk, dry intermittent fasting of Ramadan (RIF) on cardiometabolic and glucose homeostasis indicators.
Methods
Twenty meta-analyses were examined on the effects of RIF on body fat percentage (BFP), fat mass, fat-free mass, body mass index (BMI), body weight (BW), waist circumference (WC), systolic and diastolic blood pressure (SBP, DBP), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), triglycerides (TG), and very low-density lipoprotein cholesterol (VLDL-C), fasting blood glucose (FBG), glycated hemoglobin (HbA1c), insulin resistance (HOMA-IR), serum insulin, leptin, and adiponectin. Results of continuous outcomes were pooled from included meta-analyses. We employed random-effects meta-analysis using the restricted maximum likelihood method to estimate heterogeneity. P-values were derived from standard meta-analytic tests, including Egger's test for small-study effects and the excess significance test for potential publication bias. Additionally, we applied criteria from Ioannidis' evidence classification to assess the credibility of the findings.
Results
In healthy subjects, RIF was associated with significant reductions in BW (Hedges' G = -0.33; 95 % confidence interval (CI) = -0.37, -0.29; p-value = 2.63 × 10-52), WC (Hedges' G = -0.30; 95 % CI = -0.38, -0.23; p-value = 5.73 × 10-15), BFP (Hedges' G = -0.26; 95 % CI = -0.37, -0.14; p-value = 6.81 × 10-06), DBP (n = 3,456; Hedges' G = -0.26; 95 % CI = -0.38, -0.15; p-value = 9.18 × 10-06), TC (n = 9,314; Hedges' G = -0.16; 95 % CI = -0.25, -0.07; p-value = 6.27 × 10-04), and TG levels (n = 9,020; Hedges' G = -0.16; 95 % CI = -0.24, -0.08; p-value = 6.87 × 10-05). Moreover, in general population, TG (n = 16,688; Hedges' G = -0.15; 95 % CI = -0.22, -0.08; p-value <0.01) and FBG (n = 16,106; Hedges' G = -0.23; 95 % CI = -0.33, -0.13; p-value <0.01) were significantly reduced.
Conclusions
Dawn-to-dusk, dry RIF shows promise as a complementary therapy and preventive measure for reducing cardiometabolic and obesity-related risks. However, controlled studies are necessary to validate its effectiveness and fully understand its health implications.
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