Ultra-processed foods and risk of declined renal function: a dose-response meta-analysis of 786,216 participants
Hojjati Kermani MA, Awlqadr FH, Talebi S, Mehrabani S, Ghoreishy SM, Wong A, Amirian P, Zarpoosh M, Moradi S
Journal of health, population, and nutrition · 5 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
Según la declaración de financiación del texto completo.
Publicación
- Publicado
- 2025-03-17 · J Health Popul Nutr · vol. 44 · número 1 · pág. 79
- Editorial
- BioMed Central
- Citado
- 7 citas · más que el 85% de estudios similares · 2.0× el promedio de su campo
- Referencias
- 111 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY-NC-ND
- Áreas de investigación
- Consumer Attitudes and Food Labeling · Nutritional Studies and Diet · Chronic Kidney Disease and Diabetes
- Palabras clave
- ultra-processed foods, renal function decline, dose-response relationship, dietary intake, nonlinear dose-response relationship, chronic kidney disease risk
- MeSH
- kidney, humans, diet, risk factors, food handling, female, male, fast foods, food, processed
9 autores
- Mohammad Ali Hojjati Kermani🇮🇷Masih Daneshvari Hospital; Shahid Beheshti University of Medical Sciences
- Farhang Hameed Awlqadr🇮🇶Sulaimani Polytechnic University
- Sepide Talebi🇮🇷Tehran University of Medical Sciences
- Sanaz Mehrabani🇮🇷Isfahan University of Medical Sciences
- Seyed Mojtaba Ghoreishy🇮🇷Iran University of Medical Sciences
- Alexei Wong🇺🇸Marymount University
- Parsa Amirian🇮🇷Kermanshah University of Medical Sciences
- Mahsa Zarpoosh🇮🇷Kermanshah University of Medical Sciences
- Sajjad Moradi🇮🇷 · autor de correspondenciaMaragheh University of Medical Sciences
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objectives
Earlier investigations have documented an association between elevated consumption of Ultra-Processed Foods (UPFs) and adverse renal outcomes. To explore this relationship further, we executed a comprehensive dose-response meta-analysis to examine the link between UPFs intake and the risk of declined renal function.
Setting
A systematic search was completed utilizing the ISI Web of Science, Scopus, Embase as well as PubMed/MEDLINE databases (without any restrictions), up until September 5, 2024. Effect sizes of declined renal function were recalculated by applying a random effects model. The GRADE tool was adopted to assess the certainty of the evidence, while study quality and potential publication bias were examined via validated methods such as the Newcastle-Ottawa Scale, Egger's regression asymmetry and Begg's rank correlation test.
Results
Thirty-three studies (comprising 786,216 participants) were incorporated in the quantitative analysis. The results demonstrated that a greater UPFs intake was significantly associated with an enhanced risk of declined renal function (RR = 1.16; 95% CI: 1.09, 1.23; I2 = 68.8%; p 2 = 80.9%; p = 0.013; n = 9). A positive, linear association between UPF intake and the risk of declined renal function (Pnonlinearity = 0.107, Pdose-response < 0.001) was further displayed in the non-linear dose-response analysis.
Conclusion
Greater exposure to UPFs is positively associated with the risk of declined renal function. The information emphasizes the importance of considering UPFs in the prevention and management of adverse renal outcomes.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC-ND).
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.