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Ensayo controlado aleatorizado2025Acceso abierto

Psychobiological Stress Regulation in Depressive Women Achieved Through Group Music Therapy: Results From the Randomised-Controlled Music Therapy for Depression Study

Gaebel C, Jarczok MN, Aguilar-Raab C, Rittner S, Warth M, Stoffel M, Ditzen B

Stress and health : journal of the International Society for the Investigation of Stress · 3 citas

Cómo se estudió

Diseño
Ensayo controlado aleatorizado (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento

Quién lo pagó

Financiación
Financiación independiente
Organización sin fines de lucro
Joachim Herz Stiftung
Gobierno
Deutscher Akademischer Austauschdienst
Universidad u hospital
Medizinischen Fakultät Heidelberg, Universität Heidelberg
Universidad u hospital
Graduiertenakademie, Technische Universität Dresden
Organización sin fines de lucro
Christiane Nüsslein-Volhard-Stiftung
Gobierno
German Academic Exchange Service
Universidad u hospital
Graduate Academy of Heidelberg University
Organización sin fines de lucro
Steffen Lohrer Foundation
Organización sin fines de lucro
Andreas Tobias Kind Foundation
Organización sin fines de lucro
German Society for Behavioural Medicine and Behaviour Modification
Organización sin fines de lucro
Stiftung Atemweg
Organización sin fines de lucro
Dr. Walter and Luise Freundlich Foundation
Organización sin fines de lucro
German Music Therapy Society

Según 13 financiadores declarados y la declaración de financiación del texto completo.

Publicación

Publicado
2025-03-22 · Stress Health · vol. 41 · número 2 · pág. e70026
Editorial
Wiley
Citado
4 citas · más que el 93% de estudios similares · 4.4× el promedio de su campo
Impacto
Entre el 10 % más citado de su campo
Referencias
75 trabajos
Acceso
Acceso abierto (revista híbrida) · CC-BY
Áreas de investigación
Music Therapy and Health · Art Therapy and Mental Health · Neuroscience and Music Perception
Palabras clave
major depressive disorder, music therapy, group music therapy, women, stress regulation, chronic stress, stress coping, daily stress, salivary cortisol, heart rate variability, positive thinking
MeSH
saliva, humans, hydrocortisone, music therapy, adaptation, psychological, stress, psychological, psychotherapy, group, heart rate, adolescent, adult, aged, middle aged, female, young adult, major depressive disorder

7 autores

  • Christine Gaebel🇩🇪 · autor de correspondenciaHeidelberg University; University Hospital Heidelberg
  • Marc Nicolas Jarczok🇩🇪University Hospital Ulm
  • Corina Aguilar‐Raab🇩🇪University of Mannheim
  • Sabine Rittner🇩🇪Heidelberg University; University Hospital Heidelberg
  • Marco Warth🇩🇪SRH University of Applied Sciences Heidelberg
  • Martin Stoffel🇩🇪Heidelberg University; University Hospital Heidelberg
  • Beate Ditzen🇩🇪 · autor de correspondenciaHeidelberg University; University Hospital Heidelberg

Resumen

El texto original del estudio, en el idioma en que se publicó.

Major depressive disorder (MDD) is a stress-related disease that affects women more often than men. Music therapy (MT) has been shown to be effective in the treatment of MDD. However, clinical trials investigating the effects of MT on psychological and psychobiological stress-related outcomes in women suffering from MDD are still scarce. This study was conducted as a randomised controlled trial, with participants assigned to either an intervention group (IG), which received group MT (GMT), or a waitlist control group (CG), which received GMT 6 months later. The primary objective was to assess the impact of GMT on psychological stress outcomes (chronic stress, stress coping, and stress experienced in daily life) and psychobiological stress markers (diurnal salivary cortisol levels and circadian heart rate variability), considering the effects of both group allocation and time. Outcome measurements were taken before, immediately after, and-for some variables-10 weeks following the intervention period. A total of 102 women 18-65 years old and diagnosed with current MDD took part in the study. Overall, the IG demonstrated significantly stronger stress-reducing effects than the CG. Significant improvements were observed in general stress coping, positive thinking, daily life stress, and cortisol levels. GMT is a cost-effective and non-invasive approach to effectively address the stress-related psychological and psychobiological burden associated with MDD. To demonstrate long-term effects and gain a better understanding of the underlying mechanisms, further methodologically robust studies are needed. TRAIL REGISTRATION: The MUSED study was pre-registered at the German Clinical Trials Registry (DRKS00016616). All study-related procedures were published in detail in a study protocol.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).

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