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Estudio de cohortes2025Financiado por la industriaCuestionario de frecuencia de consumoSin ajuste declarado por estilo de vidaAcceso abierto

Financiado en parte por Novo Nordisk, Novo Nordisk Fonden, Novo Nordisk Fonden (Novo Nordisk Foundation)

Optimal dietary patterns for healthy aging

Tessier AJ, Wang F, Korat AA, Eliassen AH, Chavarro J, Grodstein F, Li J, Liang L, Willett WC, Sun Q, Stampfer MJ, Hu FB, Guasch-Ferré M

Nature medicine · 187 citas

Etiquetas de revisión

Cuestionario de frecuencia de consumoFinanciado por la industriaSin ajuste declarado por estilo de vida

Datos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.

Cómo se estudió

Diseño
Estudio de cohortes (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Eventos clínicos como enfermedad o muerte
Consumo medido con
Cuestionario de frecuencia de consumo

Quién lo pagó

Financiación
Financiado por la industria
Gobierno
U.S. Department of Health and Human Services
Gobierno
U.S. Department of Agriculture
Gobierno
Government of Canada
Empresa
Novo Nordisk
Empresa
Novo Nordisk Fonden
Gobierno
National Institutes of Health
Gobierno
Canadian Institutes of Health Research
Gobierno
National Institute on Aging
Gobierno
National Heart, Lung, and Blood Institute
Gobierno
National Cancer Institute
Gobierno
National Institute of Diabetes and Digestive and Kidney Diseases
Gobierno
National Center for Advancing Translational Sciences
Gobierno
U.S. Department of Health & Human Services | National Institutes of Health
Gobierno
Gouvernement du Canada | Canadian Institutes of Health Research
Empresa
Novo Nordisk Fonden (Novo Nordisk Foundation)
Gobierno
U.S. Department of Health & Human Services | National Institutes of Health (NIH)
Gobierno
NCI NIH HHS
Gobierno
NIDDK NIH HHS
Gobierno
NHLBI NIH HHS
Gobierno
NCATS NIH HHS
Gobierno
NIA NIH HHS
Subvenciones
National Cancer Institute (U01 CA167552); National Center for Advancing Translational Sciences (1K12TR004384); National Cancer Institute (P01 CA087969); National Heart, Lung, and Blood Institute (R01-HL034594); National Cancer Institute (UM1 CA186107); U.S. Department of Health and Human Services (UM1 CA186107); National Heart, Lung, and Blood Institute (R01 HL035464); National Center for Advancing Translational Sciences (K12 TR004384); U.S. Department of Health and Human Services (U01 CA167552); National Heart, Lung, and Blood Institute (R01-HL-088521); U.S. Department of Agriculture (58–8050-3-003); National Institutes of Health (3u01ca167552-09s1); National Institutes of Health (5r01hl035464-33); Canadian Institutes of Health Research (P01 CA87969); National Institute of Diabetes and Digestive and Kidney Diseases (U01 CA167552); Novo Nordisk Fonden (NNF23SA 0084103); U.S. Department of Health and Human Services (P01 CA87969); National Institutes of Health (3um1ca186107-03s1); National Center for Advancing Translational Sciences (UM1 CA186107); U.S. Department of Health and Human Services (R01 HL35464); National Institute of Diabetes and Digestive and Kidney Diseases (R00DK122128); National Institutes of Health (2p01ca087969-06); Canadian Institutes of Health Research (UM1 CA186107); Novo Nordisk (NNF23SA0084103); National Institutes of Health (U01-CA167552); National Institutes of Health (R01‐HL‐088521); National Institutes of Health (1K12TR004384); National Institutes of Health (P01 CA 87969); National Institutes of Health (R01 HL034594); National Institutes of Health (HL034594); National Institutes of Health (R01HL35464); National Institutes of Health (UM1‐CA‐186107); National Institutes of Health (CA-167552); National Institutes of Health (CA186107); National Institutes of Health (CA 87969); National Institutes of Health (HL088521); National Institutes of Health (HL35464); National Institute on Aging (R01 AG087356); National Institute of Diabetes and Digestive and Kidney Diseases (HL034594)

Según 21 financiadores declarados y la declaración de financiación del texto completo.

Publicación

Publicado
2025-03-24 · Nat Med · vol. 31 · número 5 · págs. 1644–1652
Editorial
Nature Portfolio
Citado
208 citas · más que el 100% de estudios similares · 184.6× el promedio de su campo
Impacto
Entre el 10 % más citado de su campo
Referencias
63 trabajos
Acceso
Acceso abierto (revista híbrida) · CC-BY-NC-ND
Áreas de investigación
Nutritional Studies and Diet · Diet and metabolism studies · Agriculture Sustainability and Environmental Impact
Palabras clave
Healthy aging, Gerontology, Medicine, Biology
MeSH
humans, diet, longitudinal studies, feeding behavior, aging, adult, aged, middle aged, female, male, surveys and questionnaires, healthy aging, diet, healthy

13 autores

  • Anne‐Julie Tessier🇺🇸🇨🇦 · autor de correspondenciaHarvard University; Montreal Heart Institute; Université du Québec; Université de Montréal
  • Fenglei Wang🇺🇸Harvard University
  • Andres Ardisson Korat🇺🇸Tufts University
  • A. Heather Eliassen🇺🇸Brigham and Women's Hospital; Harvard University
  • Jorge E. Chavarro🇺🇸Brigham and Women's Hospital; Harvard University
  • Francine Grodstein🇺🇸Rush University Medical Center
  • Jun Li🇺🇸Brigham and Women's Hospital; Harvard University
  • Liming Liang🇺🇸Harvard University
  • Walter Churchill Willett🇺🇸Brigham and Women's Hospital; Harvard University
  • Qi Sun🇺🇸Brigham and Women's Hospital; Harvard University
  • Meir J. Stampfer🇺🇸Brigham and Women's Hospital; Harvard University
  • Frank B. Hu🇺🇸 · autor de correspondenciaBrigham and Women's Hospital; Harvard University
  • Marta Liu Guasch-Ferré🇩🇰🇺🇸 · autor de correspondenciaUniversity of Copenhagen; Harvard University; Novo Nordisk Foundation

Resumen

El texto original del estudio, en el idioma en que se publicó.

As the global population ages, it is critical to identify diets that, beyond preventing noncommunicable diseases, optimally promote healthy aging. Here, using longitudinal questionnaire data from the Nurses' Health Study (1986-2016) and the Health Professionals Follow-Up Study (1986-2016), we examined the association of long-term adherence to eight dietary patterns and ultraprocessed food consumption with healthy aging, as assessed according to measures of cognitive, physical and mental health, as well as living to 70 years of age free of chronic diseases. After up to 30 years of follow-up, 9,771 (9.3%) of 105,015 participants (66% women, mean age = 53 years (s.d. = 8)) achieved healthy aging. For each dietary pattern, higher adherence was associated with greater odds of healthy aging and its domains. The odds ratios for the highest quintile versus the lowest ranged from 1.45 (95% confidence interval (CI) = 1.35-1.57; healthful plant-based diet) to 1.86 (95% CI = 1.71-2.01; Alternative Healthy Eating Index). When the age threshold for healthy aging was shifted to 75 years, the Alternative Healthy Eating Index diet showed the strongest association with healthy aging, with an odds ratio of 2.24 (95% CI = 2.01-2.50). Higher intakes of fruits, vegetables, whole grains, unsaturated fats, nuts, legumes and low-fat dairy products were linked to greater odds of healthy aging, whereas higher intakes of trans fats, sodium, sugary beverages and red or processed meats (or both) were inversely associated. Our findings suggest that dietary patterns rich in plant-based foods, with moderate inclusion of healthy animal-based foods, may enhance overall healthy aging, guiding future dietary guidelines.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC-ND).

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