Effects of time-restricted eating on actigraphy-derived sleep parameters: post hoc analysis of a randomized, isocaloric feeding study
Duan D, Pham LV, Jun JC, Turkson-Ocran RA, Pilla SJ, Clark JM, Maruthur NM
Sleep · 0 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Organización sin fines de lucro
- American Heart Association
- Gobierno
- National Institutes of Health
- Gobierno
- National Heart, Lung, and Blood Institute
- Gobierno
- National Institute of Diabetes and Digestive and Kidney Diseases
- Gobierno
- NIDDK NIH HHS
- Gobierno
- NHLBI NIH HHS
- Subvenciones
- American Heart Association (17SFRN33590069 and 17SFRN33560006); American Heart Association (17SFRN33560006); American Heart Association (17SFRN33590069); National Institutes of Health (17SFRN33560006); National Heart, Lung, and Blood Institute (K23HL155730); National Institute of Diabetes and Digestive and Kidney Diseases (K23DK133690)
Según 6 financiadores declarados.
Publicación
- Publicado
- 2025-03-31 · Sleep · vol. 48 · número 9
- Editorial
- Oxford University Press
- Citado
- 0 citas · más que el 8% de estudios similares · 0.0× el promedio de su campo
- Referencias
- 43 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Dietary Effects on Health · Sleep and related disorders · Circadian rhythm and melatonin
- Palabras clave
- time-restricted eating, sleep timing, sleep duration, sleep onset, sleep midpoint, sleep continuity, actigraphy, obesity, prediabetes, diabetes mellitus, meal timing, dietary intervention, weight loss, cardiometabolic risk factors, isocaloric feeding, circadian rhythm, sleep-wake patterns, Black people, women, older adults
- MeSH
- humans, obesity, fasting, sleep, time factors, adult, middle aged, female, male, actigraphy
7 autores
- Daisy Duan🇺🇸 · autor de correspondenciaJohns Hopkins University; Johns Hopkins Medicine
- Luu V. Pham🇺🇸Johns Hopkins University; Johns Hopkins Medicine
- Jonathan C. Jun🇺🇸Johns Hopkins University; Johns Hopkins Medicine
- Ruth‐Alma Turkson‐Ocran🇺🇸Beth Israel Deaconess Medical Center
- Scott J. Pilla🇺🇸Johns Hopkins University; Johns Hopkins Medicine
- Jeanne M. Clark🇺🇸Rutgers, The State University of New Jersey
- Nisa M. Maruthur🇺🇸Johns Hopkins University; Johns Hopkins Medicine
Resumen
El texto original del estudio, en el idioma en que se publicó.
Study objectives
Time-restricted eating (TRE) is a novel dietary intervention targeting weight loss and cardiometabolic risk factors. The impact of TRE on sleep patterns remains under-explored.
Methods
This was a post hoc analysis of a parallel-arm, controlled feeding trial in 41 adults with obesity and prediabetes/diabetes, randomized to TRE (08:00 am-06:00 pm) or usual eating pattern (UEP; 08:00 am-12:00 am) for 12 weeks. We objectively determined sleep-wake patterns from 7-day wrist actigraphy data obtained at baseline and week 12. From this data, we derived total sleep time (TST) and sleep midpoint over a 24-hour period, sleep onset/offset, and sleep continuity measures. We used paired t-tests or Wilcoxon signed rank tests to compare data between baseline and week 12 within intervention arms and Mann-Whitney U tests or Wilcoxon signed rank tests to compare changes between intervention arms.
Results
38 participants (20 UEP; 18 TRE; 93% of those randomized in the parent trial) with adequate actigraphy data (mean age 59.6 ± 7.3 years, 92% female, 92% Black, mean BMI 36.3 ± 4.7 kg/m2) were analyzed. Compared to UEP, TRE increased TST by 55 minutes (p = .03). TRE shifted sleep midpoint to 44 minutes earlier, from 03:24 am to 02:40 am (p = .01), while UEP maintained the same sleep midpoint at 03:15 am. Sleep onset shifted from a median of 12:22 am to 11:52 pm in TRE (p = .03) while it remained stable in UEP (p = .97). There were no differences in sleep offset and sleep continuity within and between intervention arms.
Conclusions
TRE increased sleep time and caused earlier sleep onset compared to UEP, revealing how the timing of eating may affect sleep timing and duration.
Clinical trial
The Time Restricted Intake of Meals Study (TRIM). URL: https://clinicaltrials.gov/study/NCT03527368?tab=history&a=4.
Registration
NCT03527368.
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