Efficacy of single vision spectacles combined with low-level red-light therapy in myopic amblyopia for children aged 4-8
Li L, Liao Y, Wang W, Xiong Y, Li Q, Zhang L, Wang X
Photodiagnosis and photodynamic therapy · 5 citas
Etiquetas de revisión
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Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2025-04-17 · Photodiagnosis Photodyn Ther · vol. 54 · pág. 104584
- Editorial
- Elsevier BV
- Citado
- 6 citas · más que el 93% de estudios similares · 3.8× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 39 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY-NC-ND
- Áreas de investigación
- Ophthalmology and Visual Impairment Studies · Retinopathy of Prematurity Studies · Visual perception and processing mechanisms
- Palabras clave
- Medicine, Optometry, Low vision, Ophthalmology
- MeSH
- humans, amblyopia, myopia, refraction, ocular, treatment outcome, prospective studies, eyeglasses, visual acuity, child, child, preschool, female, male, low-level light therapy
7 autores
- Lin Li🇨🇳Xuzhou Medical College
- Ya Liao🇨🇳Xuzhou Medical College; Xuzhou No.1 People's Hospital
- Wei Wang🇨🇳Xuzhou Medical College
- Yinghui Xiong🇨🇳Xuzhou Medical College; Xuzhou No.1 People's Hospital
- Qin Li🇨🇳Xuzhou Medical College; Xuzhou No.1 People's Hospital
- Lin Zhang🇨🇳China University of Mining and Technology
- Xiaojuan Wang🇨🇳Xuzhou Medical College; Shanghai First People's Hospital; Xuzhou No.1 People's Hospital
Resumen
El texto original del estudio, en el idioma en que se publicó.
Purpose
This study evaluated the efficacy and safety of Low-Level Red Light(LLRL) therapy for improving amblyopia and controlling myopia in children aged 4-8 years with myopic amblyopia.
Methods
A prospective clinical trial with 66 children, conducted from September 2023 to May 2024, included those with Spherical Equivalent Refraction (SER = sphere power + ½ cylinder power) ≤ -0.50 D and astigmatism ≤ 2.50 D, excluding pathological myopia cases. Participants were randomly assigned to Single Vision Spectacle (SVS) or LLRL groups. All wore SVS daily, while the LLRL group also received LLRL therapy (2.0 ± 0.5 mW, 650±10 nm) twice daily. The main outcomes included Best Corrected Visual Acuity (BCVA) and myopia progression, assessed by Axial Length(AL) and SER at the 1st, 3rd, and 6th months.
Results
At the six-month follow-up, both groups showed improved BCVA. The LLRL group's BCVA improved from 0.30 (0.20,0.40) to 0.10 (0.00, 0.30), while the SVS group improved from 0.40 (0.30, 0.40) to 0.30 (0.10, 0.40). Regarding myopia progression, there was no significant change in AL and SER in the LLRL group, while in the SVS group, AL increased from 24.01±0.70 mm to 24.21±0.67 mm, and SER changed from -2.75 (-4.50, -1.75) D to -3.75 (-5.25, -2.00) D. Changes in AL and SER at 1, 3, and 6 months were significantly lower in the LLRL group compared to the SVS group.
Conclusions
LLRL and optical correction both treat myopic amblyopia in young children. LLRL accelerates visual acuity improvement and effectively retards axial elongation, better controlling myopia progression compared to optical correction alone.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC-ND).
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