Effectiveness of 8-hour time-restricted eating combined with different dietary patterns on body composition, lipid metabolism, and oxidative stress in healthy adults: An exploratory study from an RCT
Liang X, Zhou Y, Kong Y, Liu J, Li K, Xue L, Yao S
Nutrition (Burbank, Los Angeles County, Calif.) · 1 cita
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- China-Japan Friendship Hospital
- Subvenciones
- China-Japan Friendship Hospital (PYBZ1815)
Según 1 financiador declarado.
Publicación
- Publicado
- 2025-03-23 · Nutrition · vol. 136 · pág. 112776
- Editorial
- Elsevier BV
- Citado
- 1 cita · más que el 62% de estudios similares · 0.5× el promedio de su campo
- Referencias
- 34 trabajos
- Acceso
- De pago
- Áreas de investigación
- Dietary Effects on Health · Nutritional Studies and Diet · Diet and metabolism studies
- Palabras clave
- time-restricted eating, ultra-processed foods, vegetarian diet, body composition, lipid metabolism, oxidative stress, malondialdehyde, 4-hydroxynonenal, superoxide dismutase, glutathione, catalase, HDL cholesterol, weight loss, waist circumference, healthy adults
- MeSH
- humans, lipids, body mass index, fasting, feeding behavior, body composition, oxidative stress, diet, vegetarian, adult, middle aged, female, male, lipid metabolism, waist circumference, young adult
7 autores
- Xinzheng Liang🇨🇳Beihang University
- Yuan-Chen Zhou🇨🇳Westlake University; Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine
- Youjia Kong🇨🇳Beijing University of Chinese Medicine
- Jixiang Liu🇨🇳Beijing University of Chinese Medicine
- Kaimin Li🇨🇳Beihang University
- Lijun Xue🇨🇳Beihang University
- Shukun Yao🇨🇳 · autor de correspondenciaChina-Japan Friendship Hospital; Beihang University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objectives
To evaluate the effectiveness of a 4-week intervention of time-restricted eating (TRE) alone or in combination with an elimination of ultra-processed foods or vegetarian diet, on body composition, lipid metabolism, and oxidative stress.
Methods
This was a randomized controlled trial including 70 participants comparing three diet groups maintained for a 4-week period: A, TRE alone; B, TRE with elimination of ultra-processed foods; and C, TRE with a vegetarian diet. Per-protocol analyses of body composition, plasma lipid levels, and oxidative stress markers were performed.
Results
Compared to baseline, Group B significantly reduced weight (P = 0.02), body mass index, waist and hip circumference, as well as fat ratio, total cholesterol, 4-hydroxynonenal an 8-Iso prostaglandin F 2α (all P < 0.05). Group B also increased high-density lipoprotein cholesterol (P < 0.05) and catalase (P = 0.002). Compared to Group A, Group B was more effective in decreasing body mass index (Δ: -0.1 ± 0.7 vs. -0.2 ± 0.3, respectively, P = 0.041) and waist circumference (Δ: -1.1 ± 4.0 vs. -3.5 ± 4.4, P < 0.001). Compared to Group A and B, the increase in superoxide dismutase (Δ: 12.74 ± 8.34, P < 0.05) and glutathione (Δ: 0.63 ± 0.40, P < 0.05) was significantly greater for Group C. Group C also produced a greater decrease in malondialdehyde (Δ: -0.79 ± 0.28) than the Group A (Δ: -0.32 ± 0.51, P < 0.001) and Group B (Δ: -0.20 ± 0.68, P < 0.001) diets.
Conclusions
Consumption of ultra-processed foods can increase body composition and lipid profile, despite TRE. A vegetarian diet in combination with TRE is effective in reducing oxidative stress injury.
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